Ctsl Mouse shRNA Plasmid (Locus ID 13039)
Specifications
| Product Data | |
| Locus ID | 13039 |
|---|---|
| Synonyms | 1190035F06Rik; CatL; Ctsl1; fs; ME; MEP; nkt |
| Vector | pGFP-C-shLenti |
| E. coli Selection | Chloramphenicol (34 ug/ml) |
| Mammalian Cell Selection | Puromycin |
| Format | Lentiviral plasmids |
| Components | Ctsl - Mouse, 4 unique 29mer shRNA constructs in lentiviral GFP vector(Gene ID = 13039). 5µg purified plasmid DNA per construct29-mer scrambled shRNA cassette in pGFP-C-shLenti Vector, TR30021, included for free. |
| RefSeq | BC068163, NM_009984, NM_009984.1, NM_009984.2, NM_009984.3, NM_009984.4 |
| UniProt ID | P06797 |
| Summary | This gene encodes a member of the peptidase C1 (papain) family of cysteine proteases. The encoded preproprotein is proteolytically processed to generate multiple protein products. These products include the activation peptide and the cathepsin L1 heavy and light chains. The mature enzyme appears to be important in embryonic development through its processing of histone H3 and may play a role in disease progression in a model of kidney disease. Homozygous knockout mice for this gene exhibit hair loss, skin thickening, bone and heart defects, and enhanced susceptibility to bacterial infection. A pseudogene of this gene has been identified in the genome. provided by RefSeq, Aug 2015 |
| shRNA Design | These shRNA constructs were designed against multiple splice variants at this gene locus. To be certain that your variant of interest is targeted, please contact techsupport@origene.com. If you need a special design or shRNA sequence, please utilize our custom shRNA service. |
| Storage | Store at -20°C |
| Shipping | Ambient |
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