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Col1a2 Mouse shRNA Plasmid (Locus ID 12843)

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SKU
TL500407
Col1a2 - Mouse, 4 unique 29mer shRNA constructs in lentiviral GFP vector, 5µg of each construct provided
  $1,013.00
2 Weeks*

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Specifications
Specifications
Product Data
Locus ID 12843
Synonyms AA960264; AI325291; Co; Col; Col1; Col1a-2; Cola-2; Cola2; oim
Vector pGFP-C-shLenti
E. coli Selection Chloramphenicol (34 ug/ml)
Mammalian Cell Selection Puromycin
Format Lentiviral plasmids
Components Col1a2 - Mouse, 4 unique 29mer shRNA constructs in lentiviral GFP vector(Gene ID = 12843). 5µg purified plasmid DNA per construct
29-mer scrambled shRNA cassette in pGFP-C-shLenti Vector, TR30021, included for free.
RefSeq BC007158, BC042503, NM_007743, NM_007743.1, NM_007743.2, NM_007743.3, BC012438, BC023203
UniProt ID Q01149
Summary This gene encodes the alpha-2 subunit of the fibril-forming type I collagen, the most abundant protein of bone, skin and tendon extracellular matrices. The encoded protein, in association with alpha-1 subunit, forms heterotrimeric type I procollagen that undergoes proteolytic processing during fibril formation. Mice harboring certain mutations in the encoded gene exhibit symptoms of moderate to severe forms of osteogenesis imperfecta. provided by RefSeq, Dec 2015
shRNA Design These shRNA constructs were designed against multiple splice variants at this gene locus. To be certain that your variant of interest is targeted, please contact techsupport@origene.com. If you need a special design or shRNA sequence, please utilize our custom shRNA service.
Storage Store at -20°C
Shipping Ambient
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Documents
Resources

file-alt Citations

Targeting the secreted RGDKGE collagen fragment reduces PD‑L1 by a proteasome‑dependent mechanism and inhibits tumor growth
Caron, Han, Lary et al
Oncol Rep (2023) 49 (2) DOI: 10.3892/or.2023.8481
Cited by 2
AI Summary: OriGene products, including mouse PD-L1 specific shRNAs, Coll-1α2 chain shRNAs, and control non-targeting shRNAs, were used in this study to selectively knock down target genes and investigate their roles in the regulation of PD-L1 expression and tumor growth.
Snippet: …Mouse PD-L1 specific short hairpin (sh)RNAs, Coll-1α2 chain shRNAs and control non-targeting shRNAs were obtained from OriGene Technologies, Inc. …Mouse PD-L1 specific short hairpin (sh)RNAs, Coll-1α2 chain shRNAs and control non-targeting shRNAs were obtained from OriGene Technologies, Inc
Showing 1-1 of 1 papers.
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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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