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Adam9 Mouse shRNA Plasmid (Locus ID 11502)

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SKU
TL500040
Adam9 - Mouse, 4 unique 29mer shRNA constructs in lentiviral GFP vector, 5µg of each construct provided
  $1,013.00
In Stock*

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Specifications
Specifications
Product Data
Locus ID 11502
Synonyms AU020942; MDC9; mKIAA0021; Mltng
Vector pGFP-C-shLenti
E. coli Selection Chloramphenicol (34 ug/ml)
Mammalian Cell Selection Puromycin
Format Lentiviral plasmids
Components Adam9 - Mouse, 4 unique 29mer shRNA constructs in lentiviral GFP vector(Gene ID = 11502). 5µg purified plasmid DNA per construct
29-mer scrambled shRNA cassette in pGFP-C-shLenti Vector, TR30021, included for free.
RefSeq BC047156, NM_001270996, NM_007404, NM_007404.1, NM_007404.2, NM_001270996.1, BC052710
UniProt ID Q61072
Summary Cleaves and releases a number of molecules with important roles in tumorigenesis and angiogenesis, such as TEK, KDR, EPHB4, CD40, VCAM1 and CDH5 (PubMed:19273593). May mediate cell-cell, cell-matrix interactions and regulate the motility of cells via interactions with integrins (PubMed:10825303).UniProtKB/Swiss-Prot Function
shRNA Design These shRNA constructs were designed against multiple splice variants at this gene locus. To be certain that your variant of interest is targeted, please contact techsupport@origene.com. If you need a special design or shRNA sequence, please utilize our custom shRNA service.
Storage Store at -20°C
Shipping Ambient
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Documents
Resources

file-alt Citations

Platelet integrin α6β1 controls lung metastasis through direct binding to cancer cell-derived ADAM9
Mammadova-Bach, Zigrino, Brucker et al
JCI Insight (2016) 1 (14), e88245 DOI: 10.1172/jci.insight.88245
Cited by 124
AI Summary: OriGene’s pGFP-C short hairpin RNA control (sh ctrl) lentiviral vector (TR30021) was used as a negative control in shRNA-mediated gene knockdown experiments to investigate the role of ADAM9 in platelet–tumor cell interactions.
Snippet: pGFP-C short hairpin RNA control (sh ctrl) lentiviral vector (TR30021) containing a noneffective 29-mer scrambled shRNA cassette (OriGene, CliniSciences) together with pLP1, pLP2, and pLP/VSVG vectors (Life Technologies) to obtain lentiviral particles
Showing 1-1 of 1 papers.
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