Aspa Mouse shRNA Plasmid (Locus ID 11484)
Specifications
| Product Data | |
| Locus ID | 11484 |
|---|---|
| Synonyms | Acy; Acy-; Acy-2; Acy2; nu; nur7 |
| Vector | pGFP-C-shLenti |
| E. coli Selection | Chloramphenicol (34 ug/ml) |
| Mammalian Cell Selection | Puromycin |
| Format | Lentiviral plasmids |
| Components | Aspa - Mouse, 4 unique 29mer shRNA constructs in lentiviral GFP vector(Gene ID = 11484). 5µg purified plasmid DNA per construct29-mer scrambled shRNA cassette in pGFP-C-shLenti Vector, TR30021, included for free. |
| RefSeq | BC024934, NM_023113, NM_023113.1, NM_023113.2, NM_023113.3, NM_023113.4, NM_023113.5 |
| UniProt ID | Q8R3P0 |
| Summary | This gene encodes an enzyme that deacteylates N-acetyl-L-aspartic acid (NAA) in the brain to yield acetate and L-aspartate. In humans, alterations in neuronal NAA concentration are associated with many neurodegenerative diseases (decrease associated with epilepsy, multiple sclerosis, myotrophic lateral sclerosis, and Alzheimer's disease; increase associated with Canavan disease). In mouse, mutations in this gene, which cause accumulation of NAA, result in demyelination and spongy degeneration in the CNS and serve as a pathophysiological model for Canavan disease. provided by RefSeq, Dec 2012 |
| shRNA Design | These shRNA constructs were designed against multiple splice variants at this gene locus. To be certain that your variant of interest is targeted, please contact techsupport@origene.com. If you need a special design or shRNA sequence, please utilize our custom shRNA service. |
| Storage | Store at -20°C |
| Shipping | Ambient |
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