TAK1 (MAP3K7) Human shRNA Plasmid Kit (Locus ID 6885)

SKU
TL320544
MAP3K7 - Human, 4 unique 29mer shRNA constructs in lentiviral GFP vector, 5µg of each construct provided
  $1,013.00
4 Weeks*
Specifications
Specifications
Product Data
Locus ID 6885
Synonyms CSCF; FMD2; MEKK7; TAK1; TGF1a
Vector pGFP-C-shLenti
E. coli Selection Chloramphenicol (34 ug/ml)
Mammalian Cell Selection Puromycin
Format Lentiviral plasmids
Components MAP3K7 - Human, 4 unique 29mer shRNA constructs in lentiviral GFP vector(Gene ID = 6885). 5µg purified plasmid DNA per construct
29-mer scrambled shRNA cassette in pGFP-C-shLenti Vector, TR30021, included for free.
RefSeq NM_003188, NM_145331, NM_145332, NM_145333, NM_003188.1, NM_003188.2, NM_003188.3, NM_145331.1, NM_145331.2, NM_145332.1, NM_145332.2, NM_145333.2, BC017715, BC017715.2, BM172351, NM_145333.3, NM_145332.3, NM_003188.4, NM_145331.3
UniProt ID O43318
Summary The protein encoded by this gene is a member of the serine/threonine protein kinase family. This kinase mediates the signaling transduction induced by TGF beta and morphogenetic protein (BMP), and controls a variety of cell functions including transcription regulation and apoptosis. In response to IL-1, this protein forms a kinase complex including TRAF6, MAP3K7P1/TAB1 and MAP3K7P2/TAB2; this complex is required for the activation of nuclear factor kappa B. This kinase can also activate MAPK8/JNK, MAP2K4/MKK4, and thus plays a role in the cell response to environmental stresses. Four alternatively spliced transcript variants encoding distinct isoforms have been reported. provided by RefSeq, Jul 2008
shRNA Design These shRNA constructs were designed against multiple splice variants at this gene locus. To be certain that your variant of interest is targeted, please contact techsupport@origene.com. If you need a special design or shRNA sequence, please utilize our custom shRNA service.
Storage Store at -20°C
Shipping Ambient
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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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