TAK1 (MAP3K7) Human shRNA Plasmid Kit (Locus ID 6885)

SKU TL320544

MAP3K7 - Human, 4 unique 29mer shRNA constructs in lentiviral GFP vector, 5µg of each construct provided

Product Data

• Locus ID: 6885
• Synonyms: CSCF; FMD2; MEKK7; TAK1; TGF1a
• Vector: pGFP-C-shLenti
• E. coli Selection: Chloramphenicol (34 ug/ml)
• Format: Lentiviral plasmids
• Components: MAP3K7 - Human, 4 unique 29mer shRNA constructs in lentiviral GFP vector(Gene ID = 6885). 5µg purified plasmid DNA per construct; 29-mer scrambled shRNA cassette in pGFP-C-shLenti Vector, TR30021, included for free.
• RefSeq: NM_003188, NM_145331, NM_145332, NM_145333, NM_003188.1, NM_003188.2, NM_003188.3, NM_145331.1, NM_145331.2, NM_145332.1, NM_145332.2, NM_145333.2, BC017715, BC017715.2, BM172351, NM_145333.3, NM_145332.3, NM_003188.4, NM_145331.3
• UniProt ID: O43318
• Summary: The protein encoded by this gene is a member of the serine/threonine protein kinase family. This kinase mediates the signaling transduction induced by TGF beta and morphogenetic protein (BMP), and controls a variety of cell functions including transcription regulation and apoptosis. In response to IL-1, this protein forms a kinase complex including TRAF6, MAP3K7P1/TAB1 and MAP3K7P2/TAB2; this complex is required for the activation of nuclear factor kappa B. This kinase can also activate MAPK8/JNK, MAP2K4/MKK4, and thus plays a role in the cell response to environmental stresses. Four alternatively spliced transcript variants encoding distinct isoforms have been reported. [provided by RefSeq, Jul 2008]
• shRNA Design: These shRNA constructs were designed against multiple splice variants at this gene locus. To be certain that your variant of interest is targeted, please contact techsupport@origene.com. If you need a special design or shRNA sequence, please utilize our custom shRNA service.
• Shipping: Ambient