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SYK Human shRNA Plasmid Kit (Locus ID 6850)

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SKU
TL320543
SYK - Human, 4 unique 29mer shRNA constructs in lentiviral GFP vector, 5µg of each construct provided
  $1,013.00
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Other products for "SYK or NM_001135052"

Specifications
Specifications
Product Data
Locus ID 6850
Synonyms IMD82; p72-Syk
Vector pGFP-C-shLenti
E. coli Selection Chloramphenicol (34 ug/ml)
Mammalian Cell Selection Puromycin
Format Lentiviral plasmids
Components SYK - Human, 4 unique 29mer shRNA constructs in lentiviral GFP vector(Gene ID = 6850). 5µg purified plasmid DNA per construct
29-mer scrambled shRNA cassette in pGFP-C-shLenti Vector, TR30021, included for free.
RefSeq NM_001135052, NM_001174167, NM_001174168, NM_003177, NR_024155, NR_024156, NM_003177.1, NM_003177.2, NM_003177.3, NM_003177.4, NM_003177.5, NM_003177.6, NM_001135052.1, NM_001135052.2, NM_001135052.3, NM_001174168.1, NM_001174168.2, NM_001174167.1, NM_001174167.2, BC011399, BC002962, BC002962.1, BC001645, BM019270, NM_001174168.3, NM_001135052.4, NM_001174167.3
UniProt ID P43405
Summary This gene encodes a member of the family of non-receptor type Tyr protein kinases. This protein is widely expressed in hematopoietic cells and is involved in coupling activated immunoreceptors to downstream signaling events that mediate diverse cellular responses, including proliferation, differentiation, and phagocytosis. It is thought to be a modulator of epithelial cell growth and a potential tumour suppressor in human breast carcinomas. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. provided by RefSeq, Mar 2010
shRNA Design These shRNA constructs were designed against multiple splice variants at this gene locus. To be certain that your variant of interest is targeted, please contact techsupport@origene.com. If you need a special design or shRNA sequence, please utilize our custom shRNA service.
Storage Store at -20°C
Shipping Ambient
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Documents
Resources

file-alt Citations

Distinct Signaling Pathways Regulate TREM2 Phagocytic and NFκB Antagonistic Activities
Yao, Coppola, Schweig et al
Front Cell Neurosci (2019) 13, 457 DOI: 10.3389/fncel.2019.00457
Cited by 112
AI Summary: In this study, OriGene products—specifically the Human TREM2 Myc-DDK tagged cDNA (RC221347) and Human DAP12 Myc-DDK tagged cDNA (RC208325)—were used to create an ectopic expression model in HEK293 cells, enabling the authors to investigate TREM2-dependent signaling pathways and phagocytic functions relevant to Alzheimer's disease.
FigureFigureFigure
Showing 1-1 of 1 papers.
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