PPAR gamma (PPARG) Human shRNA Plasmid Kit (Locus ID 5468)
SKU
TL320459
PPARG - Human, 4 unique 29mer shRNA constructs in lentiviral GFP vector, 5µg of each construct provided
$1,013.00
In Stock*
Specifications
| Product Data | |
| Locus ID | 5468 |
|---|---|
| Synonyms | CIMT1; GLM1; NR1C3; PPARG1; PPARG2; PPARG5; PPARgamma |
| Vector | pGFP-C-shLenti |
| E. coli Selection | Chloramphenicol (34 ug/ml) |
| Mammalian Cell Selection | Puromycin |
| Format | Lentiviral plasmids |
| Components | PPARG - Human, 4 unique 29mer shRNA constructs in lentiviral GFP vector(Gene ID = 5468). 5µg purified plasmid DNA per construct29-mer scrambled shRNA cassette in pGFP-C-shLenti Vector, TR30021, included for free. |
| RefSeq | NM_001330615, NM_005037, NM_015869, NM_138711, NM_138712, NM_001354666, NM_001354667, NM_001354668, NM_001354669, NM_001354670, NM_138712.1, NM_138712.2, NM_138712.3, NM_138711.1, NM_138711.2, NM_138711.3, NM_005037.1, NM_005037.2, NM_005037.3, NM_005037.4, NM_005037.5, NM_015869.1, NM_015869.2, NM_015869.3, NM_015869.4, BC006811, BM923992, NM_138712.4, NM_015869.5, NM_138711.4, NM_005037.6 |
| UniProt ID | P37231 |
| Summary | This gene encodes a member of the peroxisome proliferator-activated receptor (PPAR) subfamily of nuclear receptors. PPARs form heterodimers with retinoid X receptors (RXRs) and these heterodimers regulate transcription of various genes. Three subtypes of PPARs are known: PPAR-alpha, PPAR-delta, and PPAR-gamma. The protein encoded by this gene is PPAR-gamma and is a regulator of adipocyte differentiation. Additionally, PPAR-gamma has been implicated in the pathology of numerous diseases including obesity, diabetes, atherosclerosis and cancer. Alternatively spliced transcript variants that encode different isoforms have been described. provided by RefSeq, Jul 2008 |
| shRNA Design | These shRNA constructs were designed against multiple splice variants at this gene locus. To be certain that your variant of interest is targeted, please contact techsupport@origene.com. If you need a special design or shRNA sequence, please utilize our custom shRNA service. |
| Storage | Store at -20°C |
| Shipping | Ambient |
Reviews
Documents
Resources
Citations
Abscisic acid regulates dormancy of prostate cancer disseminated tumor cells in the bone marrow
Jung, Cackowski, Yumoto et al
Neoplasia (2021) 23 (1), 102-111 DOI: 10.1016/j.neo.2020.11.009
Jung, Cackowski, Yumoto et al
Neoplasia (2021) 23 (1), 102-111 DOI: 10.1016/j.neo.2020.11.009
Cited by 33
AI Summary: OriGene's PPARγ human shRNA lentiviral particles (cat no. TL320459V) were used to achieve stable knockdown of PPARγ in prostate cancer cells, enabling the authors to investigate the role of PPARγ signaling in abscisic acid-induced dormancy.
Snippet: 60665-g1) was used as an internal control for normalization of target gene expression. Stable knockdown of PPARγ Lentiviral particles with PPARγ human shRNA or negative control (cat no. TL320459V, Origene, Rockville, MD) were infected into PC3VC cells in the presence of 5 μg/mL polybrene for 48 h. Infected cells were selected for 7 d in media containing 1 μg/mL Puromycin and analyzed by
Showing 1-1 of 1 papers.
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