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DDR2 Human shRNA Plasmid Kit (Locus ID 4921)

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SKU
TL320440
DDR2 - Human, 4 unique 29mer shRNA constructs in lentiviral GFP vector, 5µg of each construct provided
  $1,013.00
In Stock*

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Other products for "DDR2 or NM_001014796"

Specifications
Specifications
Product Data
Locus ID 4921
Synonyms MIG20a; NTRKR3; TKT; TYRO10; WRCN
Vector pGFP-C-shLenti
E. coli Selection Chloramphenicol (34 ug/ml)
Mammalian Cell Selection Puromycin
Format Lentiviral plasmids
Components DDR2 - Human, 4 unique 29mer shRNA constructs in lentiviral GFP vector(Gene ID = 4921). 5µg purified plasmid DNA per construct
29-mer scrambled shRNA cassette in pGFP-C-shLenti Vector, TR30021, included for free.
RefSeq NM_001014796, NM_006182, NM_001354982, NM_001354983, NM_001014796.1, NM_006182.1, NM_006182.2, BC052998, BC052998.2, NM_001014796.3, NM_006182.4
UniProt ID Q16832
Summary This gene encodes a member of the discoidin domain receptor subclass of the receptor tyrosine kinase (RTKs) protein family. RTKs play a key role in the communication of cells with their microenvironment. The encoded protein is a collagen-induced receptor that activates signal transduction pathways involved in cell adhesion, proliferation, and extracellular matrix remodeling. This protein is expressed in numerous cell types and may alos be involved in wound repair and regulate tumor growth and invasiveness. Mutations in this gene are the cause of short limb-hand type spondylometaepiphyseal dysplasia. provided by RefSeq, Aug 2017
shRNA Design These shRNA constructs were designed against multiple splice variants at this gene locus. To be certain that your variant of interest is targeted, please contact techsupport@origene.com. If you need a special design or shRNA sequence, please utilize our custom shRNA service.
Storage Store at -20°C
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Documents
Resources

file-alt Citations

Targeting DDR2 in head and neck squamous cell carcinoma with dasatinib
von Mässenhausen, Sanders, Brägelmann et al
Int. J. Cancer (2016)
Cited by 40
AI Summary: OriGene’s pLenti-C-mGFP vector was used to clone DDR2 cDNA and generate stable DDR2-overexpressing cell lines, enabling the study of DDR2’s role and dasatinib’s therapeutic potential in head and neck squamous cell carcinoma.
Snippet: 23897) 32 . DDR2 cDNA from this vector was cloned into the pLenti-C-mGFP vector (OriGene, Rockville, MD, USA). Subsequently, FaDu and HSC-3 cells were lentivirally transduced with a DDR2 containing vector or the empty vector as control. Positive cells were ... Cite SaveSaving
Showing 1-1 of 1 papers.
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