Integrin alpha 4 (ITGA4) Human shRNA Plasmid Kit (Locus ID 3676)
Specifications
| Product Data | |
| Locus ID | 3676 |
|---|---|
| Synonyms | CD49D; IA4 |
| Vector | pGFP-C-shLenti |
| E. coli Selection | Chloramphenicol (34 ug/ml) |
| Mammalian Cell Selection | Puromycin |
| Format | Lentiviral plasmids |
| Components | ITGA4 - Human, 4 unique 29mer shRNA constructs in lentiviral GFP vector(Gene ID = 3676). 5µg purified plasmid DNA per construct29-mer scrambled shRNA cassette in pGFP-C-shLenti Vector, TR30021, included for free. |
| RefSeq | NM_000885, NM_001316312, NM_000885.1, NM_000885.2, NM_000885.3, NM_000885.4, NM_000885.5, BC016671, BC055419, BC080190, BC146277, BC156712, NM_000885.6 |
| UniProt ID | P13612 |
| Summary | The gene encodes a member of the integrin alpha chain family of proteins. Integrins are heterodimeric integral membrane proteins composed of an alpha chain and a beta chain that function in cell surface adhesion and signaling. The encoded preproprotein is proteolytically processed to generate light and heavy chains that comprise the alpha 4 subunit. This subunit associates with a beta 1 or beta 7 subunit to form an integrin that may play a role in cell motility and migration. This integrin is a therapeutic target for the treatment of multiple sclerosis, Crohn's disease and inflammatory bowel disease. Alternative splicing results in multiple transcript variants. provided by RefSeq, Oct 2015 |
| shRNA Design | These shRNA constructs were designed against multiple splice variants at this gene locus. To be certain that your variant of interest is targeted, please contact techsupport@origene.com. If you need a special design or shRNA sequence, please utilize our custom shRNA service. |
| Storage | Store at -20°C |
| Shipping | Ambient |
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