CAMK2A Human shRNA Plasmid Kit (Locus ID 815)
Specifications
| Product Data | |
| Locus ID | 815 |
|---|---|
| Synonyms | CAMKA; CaMKIIalpha; CaMKIINalpha; MRD53; MRT63 |
| Vector | pGFP-C-shLenti |
| E. coli Selection | Chloramphenicol (34 ug/ml) |
| Mammalian Cell Selection | Puromycin |
| Format | Lentiviral plasmids |
| Components | CAMK2A - Human, 4 unique 29mer shRNA constructs in lentiviral GFP vector(Gene ID = 815). 5µg purified plasmid DNA per construct29-mer scrambled shRNA cassette in pGFP-C-shLenti Vector, TR30021, included for free. |
| RefSeq | NM_015981, NM_171825, NM_171825.1, NM_171825.2, NM_015981.1, NM_015981.2, NM_015981.3, BC040457, NM_001363989, NM_001363990, NM_001369025, NM_015981.4 |
| UniProt ID | Q9UQM7 |
| Summary | The product of this gene belongs to the serine/threonine protein kinases family, and to the Ca(2+)/calmodulin-dependent protein kinases subfamily. Calcium signaling is crucial for several aspects of plasticity at glutamatergic synapses. This calcium calmodulin-dependent protein kinase is composed of four different chains: alpha, beta, gamma, and delta. The alpha chain encoded by this gene is required for hippocampal long-term potentiation (LTP) and spatial learning. In addition to its calcium-calmodulin (CaM)-dependent activity, this protein can undergo autophosphorylation, resulting in CaM-independent activity. Several transcript variants encoding distinct isoforms have been identified for this gene. provided by RefSeq, Jun 2018 |
| shRNA Design | These shRNA constructs were designed against multiple splice variants at this gene locus. To be certain that your variant of interest is targeted, please contact techsupport@origene.com. If you need a special design or shRNA sequence, please utilize our custom shRNA service. |
| Storage | Store at -20°C |
| Shipping | Ambient |
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