TIMP2 Human shRNA Plasmid Kit (Locus ID 7077)
Specifications
| Product Data | |
| Locus ID | 7077 |
|---|---|
| Synonyms | CSC-21K; DDC8 |
| Vector | pGFP-C-shLenti |
| E. coli Selection | Chloramphenicol (34 ug/ml) |
| Mammalian Cell Selection | Puromycin |
| Format | Lentiviral plasmids |
| Components | TIMP2 - Human, 4 unique 29mer shRNA constructs in lentiviral GFP vector(Gene ID = 7077). 5µg purified plasmid DNA per construct29-mer scrambled shRNA cassette in pGFP-C-shLenti Vector, TR30021, included for free. |
| RefSeq | NM_003255, NM_003255.1, NM_003255.2, NM_003255.3, NM_003255.4, BC071586, BC071586.1, BC010410, BC039613, BC040039, BC040445, BC052605, NM_003255.5 |
| UniProt ID | P16035 |
| Summary | This gene is a member of the TIMP gene family. The proteins encoded by this gene family are natural inhibitors of the matrix metalloproteinases, a group of peptidases involved in degradation of the extracellular matrix. In addition to an inhibitory role against metalloproteinases, the encoded protein has a unique role among TIMP family members in its ability to directly suppress the proliferation of endothelial cells. As a result, the encoded protein may be critical to the maintenance of tissue homeostasis by suppressing the proliferation of quiescent tissues in response to angiogenic factors, and by inhibiting protease activity in tissues undergoing remodelling of the extracellular matrix. provided by RefSeq, Jul 2008 |
| shRNA Design | These shRNA constructs were designed against multiple splice variants at this gene locus. To be certain that your variant of interest is targeted, please contact techsupport@origene.com. If you need a special design or shRNA sequence, please utilize our custom shRNA service. |
| Storage | Store at -20°C |
| Shipping | Ambient |
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