Junctional Adhesion Molecule C (JAM3) Human shRNA Plasmid Kit (Locus ID 83700)
Specifications
| Product Data | |
| Locus ID | 83700 |
|---|---|
| Synonyms | JAM-2; JAM-3; JAM-C; JAMC |
| Vector | pGFP-C-shLenti |
| E. coli Selection | Chloramphenicol (34 ug/ml) |
| Mammalian Cell Selection | Puromycin |
| Format | Lentiviral plasmids |
| Components | JAM3 - Human, 4 unique 29mer shRNA constructs in lentiviral GFP vector(Gene ID = 83700). 5µg purified plasmid DNA per construct29-mer scrambled shRNA cassette in pGFP-C-shLenti Vector, TR30021, included for free. |
| RefSeq | NM_001205329, NM_031470, NM_032801, NM_032801.2, NM_032801.3, NM_032801.4, NM_001205329.1, BC010690, BC012147, BC057284, BC063031 |
| UniProt ID | Q9BX67 |
| Summary | Tight junctions represent one mode of cell-to-cell adhesion in epithelial or endothelial cell sheets, forming continuous seals around cells and serving as a physical barrier to prevent solutes and water from passing freely through the paracellular space. The protein encoded by this immunoglobulin superfamily gene member is localized in the tight junctions between high endothelial cells. Unlike other proteins in this family, the this protein is unable to adhere to leukocyte cell lines and only forms weak homotypic interactions. The encoded protein is a member of the junctional adhesion molecule protein family and acts as a receptor for another member of this family. A mutation in an intron of this gene is associated with hemorrhagic destruction of the brain, subependymal calcification, and congenital cataracts. Alternative splicing results in multiple transcript variants.provided by RefSeq, Apr 2011 |
| shRNA Design | These shRNA constructs were designed against multiple splice variants at this gene locus. To be certain that your variant of interest is targeted, please contact techsupport@origene.com. If you need a special design or shRNA sequence, please utilize our custom shRNA service. |
| Storage | Store at -20°C |
| Shipping | Ambient |
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