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TYRO3 Human shRNA Plasmid Kit (Locus ID 7301)

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SKU
TL316973
TYRO3 - Human, 4 unique 29mer shRNA constructs in lentiviral GFP vector, 5µg of each construct provided
  $1,013.00
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Other products for "TYRO3 or NM_006293"

Specifications
Specifications
Product Data
Locus ID 7301
Synonyms BYK; Dtk; Etk-2; Rek; RSE; Sky; Tif
Vector pGFP-C-shLenti
E. coli Selection Chloramphenicol (34 ug/ml)
Mammalian Cell Selection Puromycin
Format Lentiviral plasmids
Components TYRO3 - Human, 4 unique 29mer shRNA constructs in lentiviral GFP vector(Gene ID = 7301). 5µg purified plasmid DNA per construct
29-mer scrambled shRNA cassette in pGFP-C-shLenti Vector, TR30021, included for free.
RefSeq NM_006293, NM_001330264, NM_006293.1, NM_006293.2, NM_006293.3, BC051756, BC051756.1, BC029925, BC034960, BC049368, NM_006293.4
UniProt ID Q06418
Summary The gene is part of a 3-member transmembrane receptor kinase receptor family with a processed pseudogene distal on chromosome 15. The encoded protein is activated by the products of the growth arrest-specific gene 6 and protein S genes and is involved in controlling cell survival and proliferation, spermatogenesis, immunoregulation and phagocytosis. The encoded protein has also been identified as a cell entry factor for Ebola and Marburg viruses. provided by RefSeq, May 2010
shRNA Design These shRNA constructs were designed against multiple splice variants at this gene locus. To be certain that your variant of interest is targeted, please contact techsupport@origene.com. If you need a special design or shRNA sequence, please utilize our custom shRNA service.
Storage Store at -20°C
Shipping Ambient
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Documents
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file-alt Citations

Oncogenic role of TYRO3 receptor tyrosine kinase in the progression of pancreatic cancer
Morimoto, Horikoshi, Nakaso et al
Cancer Lett. (2019) 470, 149-160 DOI: 10.1016/j.canlet.2019.11.028
AI Summary: OriGene’s pGFP-C-shLenti lentiviral shRNA vector (TL316973) was used in this study to silence TYRO3 expression in pancreatic cancer cells, enabling the authors to investigate TYRO3’s role in cancer progression.
Snippet: The lentiviral green fluorescent protein vector, pGFP-C-shLenti, was constructed with four unique 29mer shRNA #AD (TL316973;OriGene Technologies, Rockville, MD) (Supplementary Table 2). Twenty-four h after seeding in a 6-well plate (5.0 × 10 6 cells/well), Lenti-X 293T;;- The lentiviral green fluorescent protein vector, pGFP-C-shLenti, was constructed with four unique 29mer shRNA #AD (TL316973;OriGene Technologies, Rockville, MD) (Supplementary Table 2). …
Showing 1-1 of 1 papers.
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