MAFG Human shRNA Plasmid Kit (Locus ID 4097)
Specifications
| Product Data | |
| Locus ID | 4097 |
|---|---|
| Synonyms | hMAF |
| Vector | pGFP-C-shLenti |
| E. coli Selection | Chloramphenicol (34 ug/ml) |
| Mammalian Cell Selection | Puromycin |
| Format | Lentiviral plasmids |
| Components | MAFG - Human, 4 unique 29mer shRNA constructs in lentiviral GFP vector(Gene ID = 4097). 5µg purified plasmid DNA per construct29-mer scrambled shRNA cassette in pGFP-C-shLenti Vector, TR30021, included for free. |
| RefSeq | NM_002359, NM_032711, NM_002359.1, NM_002359.2, NM_002359.3, BC012327, BC012327.1, BC006143, BC103722, BM721518, NM_032711.4, NM_002359.4 |
| UniProt ID | O15525 |
| Summary | Globin gene expression is regulated through nuclear factor erythroid-2 (NFE2) elements located in enhancer-like locus control regions positioned many kb upstream of alpha- and beta-gene clusters (summarized by Blank et al., 1997 PubMed 9166829). NFE2 DNA-binding activity consists of a heterodimer containing a ubiquitous small Maf protein (MafF, MIM 604877; MafG; or MafK, MIM 600197) and the tissue-restricted protein p45 NFE2 (MIM 601490). Both subunits are members of the activator protein-1-like superfamily of basic leucine zipper (bZIP) proteins (see MIM 165160).supplied by OMIM, Mar 2010 |
| shRNA Design | These shRNA constructs were designed against multiple splice variants at this gene locus. To be certain that your variant of interest is targeted, please contact techsupport@origene.com. If you need a special design or shRNA sequence, please utilize our custom shRNA service. |
| Storage | Store at -20°C |
| Shipping | Ambient |
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