MPRIP Human shRNA Plasmid Kit (Locus ID 23164)

SKU
TL315724
MPRIP - Human, 4 unique 29mer shRNA constructs in lentiviral GFP vector, 5µg of each construct provided
  $1,013.00
2 Weeks*
Specifications
Specifications
Product Data
Locus ID 23164
Synonyms M-RIP; MRIP; p116Rip; RHOIP3; RIP3
Vector pGFP-C-shLenti
E. coli Selection Chloramphenicol (34 ug/ml)
Mammalian Cell Selection Puromycin
Format Lentiviral plasmids
Components MPRIP - Human, 4 unique 29mer shRNA constructs in lentiviral GFP vector(Gene ID = 23164). 5µg purified plasmid DNA per construct
29-mer scrambled shRNA cassette in pGFP-C-shLenti Vector, TR30021, included for free.
RefSeq NM_015134, NM_201274, NM_015134.1, NM_015134.2, NM_015134.3, NM_201274.1, NM_201274.2, NM_201274.3, BC009982, BC012426, BC014102, BC021058, BC021070, BC030255, BC050323, BC063588, BC075847, BC105987, BC136479, NM_001364716, NM_201274.4, NM_015134.4
UniProt ID Q6WCQ1
Summary Targets myosin phosphatase to the actin cytoskeleton. Required for the regulation of the actin cytoskeleton by RhoA and ROCK1. Depletion leads to an increased number of stress fibers in smooth muscle cells through stabilization of actin fibers by phosphorylated myosin. Overexpression of MRIP as well as its F-actin-binding region leads to disassembly of stress fibers in neuronal cells.UniProtKB/Swiss-Prot Function
shRNA Design These shRNA constructs were designed against multiple splice variants at this gene locus. To be certain that your variant of interest is targeted, please contact techsupport@origene.com. If you need a special design or shRNA sequence, please utilize our custom shRNA service.
Storage Store at -20°C
Shipping Ambient
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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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