SAE1 Human shRNA Plasmid Kit (Locus ID 10055)
SKU
TL315567
SAE1 - Human, 4 unique 29mer shRNA constructs in lentiviral GFP vector, 5µg of each construct provided
$1,013.00
2 Weeks*
Specifications
| Product Data | |
| Locus ID | 10055 |
|---|---|
| Synonyms | AOS1; HSPC140; SUA1; UBLE1A |
| Vector | pGFP-C-shLenti |
| E. coli Selection | Chloramphenicol (34 ug/ml) |
| Mammalian Cell Selection | Puromycin |
| Format | Lentiviral plasmids |
| Components | SAE1 - Human, 4 unique 29mer shRNA constructs in lentiviral GFP vector(Gene ID = 10055). 5µg purified plasmid DNA per construct29-mer scrambled shRNA cassette in pGFP-C-shLenti Vector, TR30021, included for free. |
| RefSeq | NM_001145713, NM_001145714, NM_005500, NM_016402, NR_027280, NM_005500.1, NM_005500.2, NM_001145713.1, NM_001145714.1, NM_016402.1, BC000344, BC000344.2, BC003611, BC018271, BC128518, BC128519, NM_005500.3, NM_001145713.2, NM_001145714.2 |
| UniProt ID | Q9UBE0 |
| Summary | Posttranslational modification of proteins by the addition of the small protein SUMO (see SUMO1; MIM 601912), or sumoylation, regulates protein structure and intracellular localization. SAE1 and UBA2 (MIM 613295) form a heterodimer that functions as a SUMO-activating enzyme for the sumoylation of proteins (Okuma et al., 1999 PubMed 9920803).supplied by OMIM, Mar 2010 |
| shRNA Design | These shRNA constructs were designed against multiple splice variants at this gene locus. To be certain that your variant of interest is targeted, please contact techsupport@origene.com. If you need a special design or shRNA sequence, please utilize our custom shRNA service. |
| Storage | Store at -20°C |
| Shipping | Ambient |
Reviews
Documents
Resources
Citations
A sumoylation program is essential for maintaining the mitotic fidelity in proliferating mantle cell lymphoma cells
Hanel, Lata, Youssef et al
Exp Hematol Oncol (2022) 11 (1), 40 DOI: 10.1186/s40164-022-00293-y
Hanel, Lata, Youssef et al
Exp Hematol Oncol (2022) 11 (1), 40 DOI: 10.1186/s40164-022-00293-y
Cited by 12
AI Summary: OriGene’s SAE1 human shRNA plasmids (Cat# TL315567) were used in this study to achieve SAE1 gene knockdown in mantle cell lymphoma cells, enabling the researchers to investigate the role of sumoylation in mitotic fidelity.
Snippet: … For SAE1 knockdown, after lentiviral transduction from viruses obtained from transfection of SAE1 human shRNA plasmids (Origene, Cat#TL315567), cells were GFP sorted 1 day after transfection and downstream assays were carried out after three days from sorting. Live cell microscopy, confocal microscopy, and Proximity;- For SAE1 knockdown, after lentiviral transduction from viruses obtained from transfection of SAE1 human shRNA plasmids (Origene, Cat#TL315567), cells were GFP Save Cached
Showing 1-1 of 1 papers.
Powered by BizGenius
*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen
complexities in the preparation of your product. International customers may expect an additional 1-2 weeks
in shipping.
Related Products
- Price:
- Actual Price:
Welcome to OriGene AI!
I'm your AI-powered guide to everything OriGene.
Ask me anything:
- Product specs
- Ordering help
- Technical questions
- How to find exactly what your experiment needs
Prefer a live agent? Connect with us by clicking the green chat icon, as seen in the image below or email our team at custsupport@origene.com.
