LNK (SH2B3) Human shRNA Plasmid Kit (Locus ID 10019)
Specifications
| Product Data | |
| Locus ID | 10019 |
|---|---|
| Synonyms | IDDM20; LNK |
| Vector | pGFP-C-shLenti |
| E. coli Selection | Chloramphenicol (34 ug/ml) |
| Mammalian Cell Selection | Puromycin |
| Format | Lentiviral plasmids |
| Components | SH2B3 - Human, 4 unique 29mer shRNA constructs in lentiviral GFP vector(Gene ID = 10019). 5µg purified plasmid DNA per construct29-mer scrambled shRNA cassette in pGFP-C-shLenti Vector, TR30021, included for free. |
| RefSeq | NM_001291424, NM_005475, NM_005475.1, NM_005475.2, NM_001291424.1, BC015786, BC136451, NM_005475.3 |
| UniProt ID | Q9UQQ2 |
| Summary | This gene encodes a member of the SH2B adaptor family of proteins, which are involved in a range of signaling activities by growth factor and cytokine receptors. The encoded protein is a key negative regulator of cytokine signaling and plays a critical role in hematopoiesis. Mutations in this gene have been associated with susceptibility to celiac disease type 13 and susceptibility to insulin-dependent diabetes mellitus. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. provided by RefSeq, Apr 2014 |
| shRNA Design | These shRNA constructs were designed against multiple splice variants at this gene locus. To be certain that your variant of interest is targeted, please contact techsupport@origene.com. If you need a special design or shRNA sequence, please utilize our custom shRNA service. |
| Storage | Store at -20°C |
| Shipping | Ambient |
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