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BIRC5 Human shRNA Plasmid Kit (Locus ID 332)

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SKU
TL315477
BIRC5/Survivin - Human, 4 unique 29mer shRNA constructs in lentiviral GFP vector, 5µg of each construct provided
  $1,013.00
In Stock*

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Other products for "BIRC5 or NM_001012270"

Specifications
Specifications
Product Data
Locus ID 332
Synonyms API4; EPR-1
Vector pGFP-C-shLenti
E. coli Selection Chloramphenicol (34 ug/ml)
Mammalian Cell Selection Puromycin
Format Lentiviral plasmids
Components BIRC5/Survivin - Human, 4 unique 29mer shRNA constructs in lentiviral GFP vector(Gene ID = 332). 5µg purified plasmid DNA per construct
29-mer scrambled shRNA cassette in pGFP-C-shLenti Vector, TR30021, included for free.
RefSeq NM_001012270, NM_001012271, NM_001168, NM_001168.1, NM_001168.2, NM_001012270.1, NM_001012271.1, BC034148, BC034148.1, BC000784, BC008718, BC065497, BM476145, NM_001012271.2, NM_001012270.2
UniProt ID O15392
Summary This gene is a member of the inhibitor of apoptosis (IAP) gene family, which encode negative regulatory proteins that prevent apoptotic cell death. IAP family members usually contain multiple baculovirus IAP repeat (BIR) domains, but this gene encodes proteins with only a single BIR domain. The encoded proteins also lack a C-terminus RING finger domain. Gene expression is high during fetal development and in most tumors, yet low in adult tissues. Alternatively spliced transcript variants encoding distinct isoforms have been found for this gene. provided by RefSeq, Jun 2011
shRNA Design These shRNA constructs were designed against multiple splice variants at this gene locus. To be certain that your variant of interest is targeted, please contact techsupport@origene.com. If you need a special design or shRNA sequence, please utilize our custom shRNA service.
Storage Store at -20°C
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Documents
Resources

file-alt Citations

HAb18G/CD147 Promotes pSTAT3-Mediated Pancreatic Cancer Development via CD44s
Li, Tang, Karnak et al
Clin. Cancer Res. (2013)
AI Summary: OriGene contributed survivin lentiviral shRNA and empty vector products, which were used to manipulate survivin expression and investigate its role in HAb18G/CD147-mediated pancreatic cancer development in this study.
Snippet: CD44s siRNA and control siRNA were obtained from Page 8. - 8 - Dharmacon. The survivin lentiviral shRNA and empty vector were obtained from OriGene. The reporter plasmid pSTAT3-luc and a pGL3-Control Vector were purchased from Promega. Patient samples
Showing 1-1 of 1 papers.
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