BIRC5 Human shRNA Plasmid Kit (Locus ID 332)

SKU TL315477

BIRC5/Survivin - Human, 4 unique 29mer shRNA constructs in lentiviral GFP vector, 5µg of each construct provided

Product Data

• Locus ID: 332
• Synonyms: API4; EPR-1
• Vector: pGFP-C-shLenti
• E. coli Selection: Chloramphenicol (34 ug/ml)
• Format: Lentiviral plasmids
• Components: BIRC5/Survivin - Human, 4 unique 29mer shRNA constructs in lentiviral GFP vector(Gene ID = 332). 5µg purified plasmid DNA per construct; 29-mer scrambled shRNA cassette in pGFP-C-shLenti Vector, TR30021, included for free.
• RefSeq: NM_001012270, NM_001012271, NM_001168, NM_001168.1, NM_001168.2, NM_001012270.1, NM_001012271.1, BC034148, BC034148.1, BC000784, BC008718, BC065497, BM476145, NM_001012271.2, NM_001012270.2
• UniProt ID: O15392
• Summary: This gene is a member of the inhibitor of apoptosis (IAP) gene family, which encode negative regulatory proteins that prevent apoptotic cell death. IAP family members usually contain multiple baculovirus IAP repeat (BIR) domains, but this gene encodes proteins with only a single BIR domain. The encoded proteins also lack a C-terminus RING finger domain. Gene expression is high during fetal development and in most tumors, yet low in adult tissues. Alternatively spliced transcript variants encoding distinct isoforms have been found for this gene. [provided by RefSeq, Jun 2011]
• shRNA Design: These shRNA constructs were designed against multiple splice variants at this gene locus. To be certain that your variant of interest is targeted, please contact techsupport@origene.com. If you need a special design or shRNA sequence, please utilize our custom shRNA service.
• Shipping: Ambient