AGPAT2 Human shRNA Plasmid Kit (Locus ID 10555)

SKU
TL314894
AGPAT2 - Human, 4 unique 29mer shRNA constructs in lentiviral GFP vector, 5µg of each construct provided
  $1,013.00
In Stock*
Specifications
Specifications
Product Data
Locus ID 10555
Synonyms 1-AGPAT2; BSCL; BSCL1; LPAAB; LPAAT-beta
Vector pGFP-C-shLenti
E. coli Selection Chloramphenicol (34 ug/ml)
Mammalian Cell Selection Puromycin
Format Lentiviral plasmids
Components AGPAT2 - Human, 4 unique 29mer shRNA constructs in lentiviral GFP vector(Gene ID = 10555). 5µg purified plasmid DNA per construct
29-mer scrambled shRNA cassette in pGFP-C-shLenti Vector, TR30021, included for free.
RefSeq NM_001012727, NM_006412, NM_006412.1, NM_006412.2, NM_006412.3, NM_001012727.1, BC000026, BC004529, BC004529.2, BC007269, BC019292, NM_001012727.2, NM_006412.4
UniProt ID O15120
Summary This gene encodes a member of the 1-acylglycerol-3-phosphate O-acyltransferase family. The protein is located within the endoplasmic reticulum membrane and converts lysophosphatidic acid to phosphatidic acid, the second step in de novo phospholipid biosynthesis. Mutations in this gene have been associated with congenital generalized lipodystrophy (CGL), or Berardinelli-Seip syndrome, a disease characterized by a near absence of adipose tissue and severe insulin resistance. Alternate transcriptional splice variants, encoding different isoforms, have been characterized. provided by RefSeq, Jul 2008
shRNA Design These shRNA constructs were designed against multiple splice variants at this gene locus. To be certain that your variant of interest is targeted, please contact techsupport@origene.com. If you need a special design or shRNA sequence, please utilize our custom shRNA service.
Storage Store at -20°C
Shipping Ambient
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Documents
Resources

file-alt Citations

Terapia génica y celular para la corrección de la Lipodistrofia Congénita Generalizada
Moro Muñoz
Thesis (2014)
Snippet: Para este procedimiento se utilizaron vectores lentivirales comerciales de la colección shRNA Plasmid Panels de OriGene codificando ARNs de interferencia contra AGPAT2. Se siguieron los protocolos de producción de sobrenadantes virales y transducción celular detallados en los apartados 3 y 4
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