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ATF2 Human shRNA Plasmid Kit (Locus ID 1386)

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SKU
TL314615
ATF2 - Human, 4 unique 29mer shRNA constructs in lentiviral GFP vector, 5µg of each construct provided
  $1,013.00
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Specifications
Specifications
Product Data
Locus ID 1386
Synonyms CRE-BP1; CREB-2; CREB2; HB16; TREB7
Vector pGFP-C-shLenti
E. coli Selection Chloramphenicol (34 ug/ml)
Mammalian Cell Selection Puromycin
Format Lentiviral plasmids
Components ATF2 - Human, 4 unique 29mer shRNA constructs in lentiviral GFP vector(Gene ID = 1386). 5µg purified plasmid DNA per construct
29-mer scrambled shRNA cassette in pGFP-C-shLenti Vector, TR30021, included for free.
RefSeq NM_001256090, NM_001256091, NM_001256092, NM_001256093, NM_001256094, NM_001880, NR_045768, NR_045769, NR_045770, NR_045771, NR_045772, NR_045773, NR_045774, NM_001880.1, NM_001880.2, NM_001880.3, NM_001256094.1, NM_001256093.1, NM_001256092.1, NM_001256091.1, NM_001256090.1, BC026175, BC107698, BC130335, BC130337, NM_001880.4, NM_001256090.2, NM_001256093.2, NM_001256092.2
UniProt ID P15336
Summary This gene encodes a transcription factor that is a member of the leucine zipper family of DNA binding proteins. The encoded protein has been identified as a moonlighting protein based on its ability to perform mechanistically distinct functions This protein binds to the cAMP-responsive element (CRE), an octameric palindrome. It forms a homodimer or a heterodimer with c-Jun and stimulates CRE-dependent transcription. This protein is also a histone acetyltransferase (HAT) that specifically acetylates histones H2B and H4 in vitro; thus it may represent a class of sequence-specific factors that activate transcription by direct effects on chromatin components. The encoded protein may also be involved in cell's DNA damage response independent of its role in transcriptional regulation. Several alternatively spliced transcript variants have been found for this gene provided by RefSeq, Jan 2014
shRNA Design These shRNA constructs were designed against multiple splice variants at this gene locus. To be certain that your variant of interest is targeted, please contact techsupport@origene.com. If you need a special design or shRNA sequence, please utilize our custom shRNA service.
Storage Store at -20°C
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