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MVB12B Human shRNA Plasmid Kit (Locus ID 89853)

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SKU
TL314267
MVB12B - Human, 4 unique 29mer shRNA constructs in lentiviral GFP vector, 5µg of each construct provided
  $1,013.00
2 Weeks*

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Other products for "MVB12B or NM_001011703"

Specifications
Specifications
Product Data
Locus ID 89853
Synonyms C9orf28; FAM125B
Vector pGFP-C-shLenti
E. coli Selection Chloramphenicol (34 ug/ml)
Mammalian Cell Selection Puromycin
Format Lentiviral plasmids
Components MVB12B - Human, 4 unique 29mer shRNA constructs in lentiviral GFP vector(Gene ID = 89853). 5µg purified plasmid DNA per construct
29-mer scrambled shRNA cassette in pGFP-C-shLenti Vector, TR30021, included for free.
RefSeq BC000122, NM_001011703, NM_033446, NM_001011703.1, NM_001011703.2, NM_033446.1, NM_033446.2, BC028675, BC028675.1, BC036326, BC041601, NM_033446.3, NM_001011703.3
UniProt ID Q9H7P6
Summary The protein encoded by this gene is a component of the ESCRT-I complex, a heterotetramer, which mediates the sorting of ubiquitinated cargo protein from the plasma membrane to the endosomal vesicle. ESCRT-I complex plays an essential role in HIV budding and endosomal protein sorting. Depletion and overexpression of this and related protein (MVB12A) inhibit HIV-1 infectivity and induce unusual viral assembly defects, indicating a role for MVB12 subunits in regulating ESCRT-mediated virus budding. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. provided by RefSeq, Aug 2011
shRNA Design These shRNA constructs were designed against multiple splice variants at this gene locus. To be certain that your variant of interest is targeted, please contact techsupport@origene.com. If you need a special design or shRNA sequence, please utilize our custom shRNA service.
Storage Store at -20°C
Shipping Ambient
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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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