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CACNA1C Human shRNA Plasmid Kit (Locus ID 775)

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SKU
TL314247
CACNA1C - Human, 4 unique 29mer shRNA constructs in lentiviral GFP vector, 5µg of each construct provided
  $1,013.00
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Specifications
Specifications
Product Data
Locus ID 775
Synonyms CACH2; CACN2; CACNL1A1; CaV1.2; CCHL1A1; LQT8; TS; TS. LQT8
Vector pGFP-C-shLenti
E. coli Selection Chloramphenicol (34 ug/ml)
Mammalian Cell Selection Puromycin
Format Lentiviral plasmids
Components CACNA1C - Human, 4 unique 29mer shRNA constructs in lentiviral GFP vector(Gene ID = 775). 5µg purified plasmid DNA per construct
29-mer scrambled shRNA cassette in pGFP-C-shLenti Vector, TR30021, included for free.
RefSeq NM_000719, NM_001129827, NM_001129829, NM_001129830, NM_001129831, NM_001129832, NM_001129833, NM_001129834, NM_001129835, NM_001129836, NM_001129837, NM_001129838, NM_001129839, NM_001129840, NM_001129841, NM_001129842, NM_001129843, NM_001129844, NM_001129846, NM_001167623, NM_001167624, NM_001167625, NM_199460, NM_000719.1, NM_000719.2, NM_000719.3, NM_000719.4, NM_000719.5, NM_000719.6, NM_001129846.1, NM_001129844.1, NM_001129841.1, NM_001129842.1, NM_001129843.1, NM_001129840.1, NM_001129839.1, NM_001129837.1, NM_001129838.1, NM_001129836.1, NM_001129833.1, NM_001129834.1, NM_001129835.1, NM_001129832.1, NM_001129831.1, NM_001129830.1, NM_001129830.2, NM_001129829.1, NM_001129827.1, NM_199460.2, NM_199460.3, NM_001167623.1, NM_001167624.1, NM_001167624.2, NM_001167625.1, BC093695, BC146846, NM_001129827.2, NM_001167623.2, NM_001129840.2, NM_000719.7
UniProt ID Q13936
Summary This gene encodes an alpha-1 subunit of a voltage-dependent calcium channel. Calcium channels mediate the influx of calcium ions into the cell upon membrane polarization. The alpha-1 subunit consists of 24 transmembrane segments and forms the pore through which ions pass into the cell. The calcium channel consists of a complex of alpha-1, alpha-2/delta, beta, and gamma subunits in a 1:1:1:1 ratio. There are multiple isoforms of each of these proteins, either encoded by different genes or the result of alternative splicing of transcripts. The protein encoded by this gene binds to and is inhibited by dihydropyridine. Alternative splicing results in many transcript variants encoding different proteins. Some of the predicted proteins may not produce functional ion channel subunits. provided by RefSeq, Oct 2012
shRNA Design These shRNA constructs were designed against multiple splice variants at this gene locus. To be certain that your variant of interest is targeted, please contact techsupport@origene.com. If you need a special design or shRNA sequence, please utilize our custom shRNA service.
Storage Store at -20°C
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