CACNA2D1 Human shRNA Plasmid Kit (Locus ID 781)

SKU
TL314240
CACNA2D1 - Human, 4 unique 29mer shRNA constructs in lentiviral GFP vector, 5µg of each construct provided
  $1,013.00
2 Weeks*
Specifications
Specifications
Product Data
Locus ID 781
Synonyms CACNA2; CACNL2A; CCHL2A; LINC01112; lncRNA-N3
Vector pGFP-C-shLenti
E. coli Selection Chloramphenicol (34 ug/ml)
Mammalian Cell Selection Puromycin
Format Lentiviral plasmids
Components CACNA2D1 - Human, 4 unique 29mer shRNA constructs in lentiviral GFP vector(Gene ID = 781). 5µg purified plasmid DNA per construct
29-mer scrambled shRNA cassette in pGFP-C-shLenti Vector, TR30021, included for free.
RefSeq NM_000722, NM_001302890, NM_000722.1, NM_000722.3, NM_001302890.1, BC051339, BC117468, BC117470, NM_001366867, NM_001302890.2, NM_000722.4
UniProt ID P54289
Summary The preproprotein encoded by this gene is cleaved into multiple chains that comprise the alpha-2 and delta subunits of the voltage-dependent calcium channel complex. Calcium channels mediate the influx of calcium ions into the cell upon membrane polarization. Mutations in this gene can cause cardiac deficiencies, including Brugada syndrome and short QT syndrome. Alternate splicing results in multiple transcript variants, some of which may lack the delta subunit portion. provided by RefSeq, Nov 2014
shRNA Design These shRNA constructs were designed against multiple splice variants at this gene locus. To be certain that your variant of interest is targeted, please contact techsupport@origene.com. If you need a special design or shRNA sequence, please utilize our custom shRNA service.
Storage Store at -20°C
Shipping Ambient
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Documents
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file-alt Citations

α2δ1 may be a potential marker for cancer stem cell in laryngeal squamous cell carcinoma
Huang, Li, Zhao et al
Cancer Biomark (2019) 24 (1), 97-107 DOI: 10.3233/CBM-181947
AI Summary: OriGene contributed retroviral-based plasmids containing short hairpin RNAs (shRNA) targeting human α2δ1, which were used to investigate the role of α2δ1 in laryngeal squamous cell carcinoma in this study.
Snippet: Retroviral-based plasmids containing a short hairpin RNA (shRNA) against human α2δ1 were purchased from Origene (Rockville, MD, USA). The U6 promoter-driven shRNA expression cassettes were transferred to the lentiviral shuttle vector plenti6 (Invitrogen). Lentiviral packaging, infection, and selection of blasticidin-resistant cell pools were performed as previously described [24]. The sequences of...
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Showing 1-1 of 1 papers.
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