CBX2 Human shRNA Plasmid Kit (Locus ID 84733)

SKU
TL314173
CBX2 - Human, 4 unique 29mer shRNA constructs in lentiviral GFP vector, 5µg of each construct provided
  $1,013.00
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Specifications
Specifications
Product Data
Locus ID 84733
Synonyms CDCA6; M33; SRXY5
Vector pGFP-C-shLenti
E. coli Selection Chloramphenicol (34 ug/ml)
Mammalian Cell Selection Puromycin
Format Lentiviral plasmids
Components CBX2 - Human, 4 unique 29mer shRNA constructs in lentiviral GFP vector(Gene ID = 84733). 5µg purified plasmid DNA per construct
29-mer scrambled shRNA cassette in pGFP-C-shLenti Vector, TR30021, included for free.
RefSeq NM_005189, NM_032647, NM_032647.1, NM_032647.2, NM_032647.3, NM_005189.2, BC004252, BC119759, BC119760, BC156118, BC157074, NM_005189.3
UniProt ID Q14781
Summary This gene encodes a component of the polycomb multiprotein complex, which is required to maintain the transcriptionally repressive state of many genes throughout development via chromatin remodeling and modification of histones. Disruption of this gene in mice results in male-to-female gonadal sex reversal. Mutations in this gene are also associated with gonadal dysgenesis in humans. Alternatively spliced transcript variants encoding different isoforms have been noted for this gene.provided by RefSeq, Mar 2010
shRNA Design These shRNA constructs were designed against multiple splice variants at this gene locus. To be certain that your variant of interest is targeted, please contact techsupport@origene.com. If you need a special design or shRNA sequence, please utilize our custom shRNA service.
Storage Store at -20°C
Shipping Ambient
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Documents
Resources

file-alt Citations

H3K27me3 spreading organizes canonical PRC1 chromatin architecture to regulate developmental programs
Krug, Hu, Chen et al
bioRxiv (2023)
Cited by 5
Snippet: Short hairpin RNA (shRNA) knockdown (KD) cell lines were generated through lentiviral delivery of shRNA pools targeting CBX2 (Origene TL314173), CBX4 (Origene
Showing 1-1 of 1 papers.
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