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CCM2 Human shRNA Plasmid Kit (Locus ID 83605)

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SKU
TL314143
CCM2 - Human, 4 unique 29mer shRNA constructs in lentiviral GFP vector, 5µg of each construct provided
  $1,013.00
2 Weeks*

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Other products for "CCM2 or NM_001029835"

Specifications
Specifications
Product Data
Locus ID 83605
Synonyms C7orf22; OSM; PP10187
Vector pGFP-C-shLenti
E. coli Selection Chloramphenicol (34 ug/ml)
Mammalian Cell Selection Puromycin
Format Lentiviral plasmids
Components CCM2 - Human, 4 unique 29mer shRNA constructs in lentiviral GFP vector(Gene ID = 83605). 5µg purified plasmid DNA per construct
29-mer scrambled shRNA cassette in pGFP-C-shLenti Vector, TR30021, included for free.
RefSeq NM_001029835, NM_001167934, NM_001167935, NM_031443, NR_030770, NM_031443.1, NM_031443.2, NM_031443.3, NM_001029835.1, NM_001029835.2, NM_001167935.1, NM_001167934.1, BC004903, BC008859, BC016832, BC025958, BC063663, NM_001363458, NM_001363459, NM_031443.4
UniProt ID Q9BSQ5
Summary This gene encodes a scaffold protein that functions in the stress-activated p38 Mitogen-activated protein kinase (MAPK) signaling cascade. The protein interacts with SMAD specific E3 ubiquitin protein ligase 1 (also known as SMURF1) via a phosphotyrosine binding domain to promote RhoA degradation. The protein is required for normal cytoskeletal structure, cell-cell interactions, and lumen formation in endothelial cells. Mutations in this gene result in cerebral cavernous malformations. Multiple transcript variants encoding different isoforms have been found for this gene.provided by RefSeq, Nov 2009
shRNA Design These shRNA constructs were designed against multiple splice variants at this gene locus. To be certain that your variant of interest is targeted, please contact techsupport@origene.com. If you need a special design or shRNA sequence, please utilize our custom shRNA service.
Storage Store at -20°C
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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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