CDC45L (CDC45) Human shRNA Plasmid Kit (Locus ID 8318)
Specifications
| Product Data | |
| Locus ID | 8318 |
|---|---|
| Synonyms | CDC45L; CDC45L2; MGORS7; PORC-PI-1 |
| Vector | pGFP-C-shLenti |
| E. coli Selection | Chloramphenicol (34 ug/ml) |
| Mammalian Cell Selection | Puromycin |
| Format | Lentiviral plasmids |
| Components | CDC45 - Human, 4 unique 29mer shRNA constructs in lentiviral GFP vector(Gene ID = 8318). 5µg purified plasmid DNA per construct29-mer scrambled shRNA cassette in pGFP-C-shLenti Vector, TR30021, included for free. |
| RefSeq | NM_001178010, NM_001178011, NM_003504, NM_003504.1, NM_003504.2, NM_003504.3, NM_003504.4, NM_001178011.1, NM_001178011.2, NM_001178010.1, NM_001178010.2, BC006232, BC006232.2, BC010022, BM751026, NM_001369291, NR_161281, NM_003504.5 |
| UniProt ID | O75419 |
| Summary | The protein encoded by this gene was identified by its strong similarity with Saccharomyces cerevisiae Cdc45, an essential protein required to the initiation of DNA replication. Cdc45 is a member of the highly conserved multiprotein complex including Cdc6/Cdc18, the minichromosome maintenance proteins (MCMs) and DNA polymerase, which is important for early steps of DNA replication in eukaryotes. This protein has been shown to interact with MCM7 and DNA polymerase alpha. Studies of the similar gene in Xenopus suggested that this protein play a pivotal role in the loading of DNA polymerase alpha onto chromatin. Alternate splicing results in multiple transcript variants. provided by RefSeq, Jul 2013 |
| shRNA Design | These shRNA constructs were designed against multiple splice variants at this gene locus. To be certain that your variant of interest is targeted, please contact techsupport@origene.com. If you need a special design or shRNA sequence, please utilize our custom shRNA service. |
| Storage | Store at -20°C |
| Shipping | Ambient |
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