OriGene Logo

Customer Login

Checkout as a new customer

Creating an account has many benefits:

  • See order and shipping status
  • Track order history
  • Check out faster
Create an Account

DAB2 Human shRNA Plasmid Kit (Locus ID 1601)

Be the first to review this product
SKU
TL313573
DAB2 - Human, 4 unique 29mer shRNA constructs in lentiviral GFP vector, 5µg of each construct provided
  $1,013.00
In Stock*

Frequently Bought Together (4)

TA364745 DAB2 rabbit polyclonal antibody
100 ul
$310.00
EB200002 Lateral flow testing sticks used for the semi-quantitative detection of the lentiviral p24 protein, 20 tests
20 Tests
$450.00
TR30037 Lenti-vpak packaging kit - packaging plasmids and transfection reagent
10 reactions
$720.00
TF81001 TurboFectin Transfection Reagent (1 mL in 1 vial)
1 ml in 1 vial
$530.00

Other products for "DAB2 or NM_001244871"

Specifications
Specifications
Product Data
Locus ID 1601
Synonyms DOC-2; DOC2
Vector pGFP-C-shLenti
E. coli Selection Chloramphenicol (34 ug/ml)
Mammalian Cell Selection Puromycin
Format Lentiviral plasmids
Components DAB2 - Human, 4 unique 29mer shRNA constructs in lentiviral GFP vector(Gene ID = 1601). 5µg purified plasmid DNA per construct
29-mer scrambled shRNA cassette in pGFP-C-shLenti Vector, TR30021, included for free.
RefSeq NM_001244871, NM_001343, NM_001343.1, NM_001343.2, NM_001343.3, NM_001244871.1, BC003064, BC003064.2, NM_001343.4
UniProt ID P98082
Summary This gene encodes a mitogen-responsive phosphoprotein. It is expressed in normal ovarian epithelial cells, but is down-regulated or absent from ovarian carcinoma cell lines, suggesting its role as a tumor suppressor. This protein binds to the SH3 domains of GRB2, an adaptor protein that couples tyrosine kinase receptors to SOS (a guanine nucleotide exchange factor for Ras), via its C-terminal proline-rich sequences, and may thus modulate growth factor/Ras pathways by competing with SOS for binding to GRB2. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. provided by RefSeq, Oct 2011
shRNA Design These shRNA constructs were designed against multiple splice variants at this gene locus. To be certain that your variant of interest is targeted, please contact techsupport@origene.com. If you need a special design or shRNA sequence, please utilize our custom shRNA service.
Storage Store at -20°C
Shipping Ambient
Reviews
Write Review
 
 
 
 
 

Be the first to review this product

Please note:
Only reviews with images are eligible for a $20/20€ Amazon gift card.
Reviews without images are eligible for a $10/10€ Amazon gift card.
For more details about the terms and conditions, please visit the promotion page.

Review image
Documents
Resources

file-alt Citations

Cathepsin-B-mediated cleavage of Disabled-2 regulates TGF-β-induced autophagy
Jiang, Woosley, Sivalingam et al
Nat. Cell Biol. (2016) 18 (8), 851-63 DOI: 10.1038/ncb3388
Cited by 62
AI Summary: OriGene Technologies contributed to the study by providing Cathepsin B shRNA and Dab2 shRNA constructs, which were used to generate knockdown cells for investigating the roles of these proteins in TGF-β-induced autophagy.
Snippet: Cathepsin B shRNA and Dab2 shRNA constructs were purchased from OriGene Technologies. Dab2 KD cells were generated with a protocol supplied by OriGene Technologies
Showing 1-1 of 1 papers.
Powered by BizGenius
*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

Related Products