Dynamitin (DCTN2) Human shRNA Plasmid Kit (Locus ID 10540)
Specifications
| Product Data | |
| Locus ID | 10540 |
|---|---|
| Synonyms | DCTN50; DYNAMITIN; HEL-S-77; RBP50 |
| Vector | pGFP-C-shLenti |
| E. coli Selection | Chloramphenicol (34 ug/ml) |
| Mammalian Cell Selection | Puromycin |
| Format | Lentiviral plasmids |
| Components | DCTN2 - Human, 4 unique 29mer shRNA constructs in lentiviral GFP vector(Gene ID = 10540). 5µg purified plasmid DNA per construct29-mer scrambled shRNA cassette in pGFP-C-shLenti Vector, TR30021, included for free. |
| RefSeq | NM_001261412, NM_001261413, NM_006400, NM_001348065, NM_001348066, NM_001348067, NM_001348068, NR_145419, NM_006400.1, NM_006400.2, NM_006400.3, NM_006400.4, NM_001261413.1, NM_001261412.1, BC000718, BC009468, BC014083, NM_001261413.2 |
| UniProt ID | Q13561 |
| Summary | This gene encodes a 50-kD subunit of dynactin, a macromolecular complex consisting of 10-11 subunits ranging in size from 22 to 150 kD. Dynactin binds to both microtubules and cytoplasmic dynein. It is involved in a diverse array of cellular functions, including ER-to-Golgi transport, the centripetal movement of lysosomes and endosomes, spindle formation, chromosome movement, nuclear positioning, and axonogenesis. This subunit is present in 4-5 copies per dynactin molecule. It contains three short alpha-helical coiled-coil domains that may mediate association with self or other dynactin subunits. It may interact directly with the largest subunit (p150) of dynactin and may affix p150 in place. Multiple alternatively spliced transcript variants encoding distinct isoforms have been found for this gene. provided by RefSeq, May 2012 |
| shRNA Design | These shRNA constructs were designed against multiple splice variants at this gene locus. To be certain that your variant of interest is targeted, please contact techsupport@origene.com. If you need a special design or shRNA sequence, please utilize our custom shRNA service. |
| Storage | Store at -20°C |
| Shipping | Ambient |
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