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DKK3 Human shRNA Plasmid Kit (Locus ID 27122)

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SKU
TL313463
DKK3 - Human, 4 unique 29mer shRNA constructs in lentiviral GFP vector, 5µg of each construct provided
  $1,013.00
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Other products for "DKK3 or NM_001018057"

Specifications
Specifications
Product Data
Locus ID 27122
Synonyms REIC; RIG
Vector pGFP-C-shLenti
E. coli Selection Chloramphenicol (34 ug/ml)
Mammalian Cell Selection Puromycin
Format Lentiviral plasmids
Components DKK3 - Human, 4 unique 29mer shRNA constructs in lentiviral GFP vector(Gene ID = 27122). 5µg purified plasmid DNA per construct
29-mer scrambled shRNA cassette in pGFP-C-shLenti Vector, TR30021, included for free.
RefSeq NM_001018057, NM_001330220, NM_013253, NM_015881, NM_013253.1, NM_013253.2, NM_013253.3, NM_013253.4, NM_015881.1, NM_015881.2, NM_015881.3, NM_015881.4, NM_015881.5, NM_001018057.1, BC007660, BC007660.2
UniProt ID Q9UBP4
Summary This gene encodes a protein that is a member of the dickkopf family. The secreted protein contains two cysteine rich regions and is involved in embryonic development through its interactions with the Wnt signaling pathway. The expression of this gene is decreased in a variety of cancer cell lines and it may function as a tumor suppressor gene. Alternative splicing results in multiple transcript variants encoding the same protein. provided by RefSeq, Jul 2008
shRNA Design These shRNA constructs were designed against multiple splice variants at this gene locus. To be certain that your variant of interest is targeted, please contact techsupport@origene.com. If you need a special design or shRNA sequence, please utilize our custom shRNA service.
Storage Store at -20°C
Shipping Ambient
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Documents
Resources

file-alt Citations

DKK3 knockdown confers negative effects on the malignant potency of head and neck squamous cell carcinoma cells via the PI3K/Akt and MAPK signaling pathways
Katase, Nishimatsu, Yamauchi et al
Int. J. Oncol. (2018)
AI Summary: OriGene products, specifically the DKK3 shRNA lentiviral plasmid (cat. no. TL313463) and the control shRNA vector (cat. no. TR30021), were used to generate stable DKK3 knockdown and control cell lines, enabling the investigation of DKK3's role in the malignant behavior of head and neck squamous cell carcinoma cells.
Snippet: no. TL313463;OriGene Technologies, Inc., Rockville, MD, USA] and a control vector (non‑effective 29‑mer shScr cassette cloned into a pGFP‑C‑shLenti Vector;cat. no. TR30021;OriGene Technologies, Inc.) were purchased and used according to the manufacturer's
Showing 1-1 of 1 papers.
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