Dynamin 2 (DNM2) Human shRNA Plasmid Kit (Locus ID 1785)
Specifications
| Product Data | |
| Locus ID | 1785 |
|---|---|
| Synonyms | CMT2M; CMTDI1; CMTDIB; DI-CMTB; DYN2; DYNII; LCCS5 |
| Vector | pGFP-C-shLenti |
| E. coli Selection | Chloramphenicol (34 ug/ml) |
| Mammalian Cell Selection | Puromycin |
| Format | Lentiviral plasmids |
| Components | DNM2 - Human, 4 unique 29mer shRNA constructs in lentiviral GFP vector(Gene ID = 1785). 5µg purified plasmid DNA per construct29-mer scrambled shRNA cassette in pGFP-C-shLenti Vector, TR30021, included for free. |
| RefSeq | NM_001005360, NM_001005361, NM_001005362, NM_001190716, NM_004945, NM_004945.1, NM_004945.2, NM_004945.3, NM_001005360.1, NM_001005360.2, NM_001005361.1, NM_001005361.2, NM_001005362.1, NM_001005362.2, NM_001190716.1, BC054501, BC054501.1, BC039596, BM148999, NM_001005361.3, NM_001190716.2, NM_001005360.3 |
| UniProt ID | P50570 |
| Summary | Dynamins represent one of the subfamilies of GTP-binding proteins. These proteins share considerable sequence similarity over the N-terminal portion of the molecule, which contains the GTPase domain. Dynamins are associated with microtubules. They have been implicated in cell processes such as endocytosis and cell motility, and in alterations of the membrane that accompany certain activities such as bone resorption by osteoclasts. Dynamins bind many proteins that bind actin and other cytoskeletal proteins. Dynamins can also self-assemble, a process that stimulates GTPase activity. Five alternatively spliced transcripts encoding different proteins have been described. Additional alternatively spliced transcripts may exist, but their full-length nature has not been determined. provided by RefSeq, Jun 2010 |
| shRNA Design | These shRNA constructs were designed against multiple splice variants at this gene locus. To be certain that your variant of interest is targeted, please contact techsupport@origene.com. If you need a special design or shRNA sequence, please utilize our custom shRNA service. |
| Storage | Store at -20°C |
| Shipping | Ambient |
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