Dysferlin (DYSF) Human shRNA Plasmid Kit (Locus ID 8291)
SKU
TL313324
DYSF - Human, 4 unique 29mer shRNA constructs in lentiviral GFP vector, 5µg of each construct provided
$1,013.00
2 Weeks*
Specifications
| Product Data | |
| Locus ID | 8291 |
|---|---|
| Synonyms | FER1L1; LGMD2B; LGMDR2; MMD1 |
| Vector | pGFP-C-shLenti |
| E. coli Selection | Chloramphenicol (34 ug/ml) |
| Mammalian Cell Selection | Puromycin |
| Format | Lentiviral plasmids |
| Components | DYSF - Human, 4 unique 29mer shRNA constructs in lentiviral GFP vector(Gene ID = 8291). 5µg purified plasmid DNA per construct29-mer scrambled shRNA cassette in pGFP-C-shLenti Vector, TR30021, included for free. |
| RefSeq | NM_001130455, NM_001130976, NM_001130977, NM_001130978, NM_001130979, NM_001130980, NM_001130981, NM_001130982, NM_001130983, NM_001130984, NM_001130985, NM_001130986, NM_001130987, NM_003494, NM_003494.1, NM_003494.2, NM_003494.3, NM_001130976.1, NM_001130986.1, NM_001130455.1, NM_001130977.1, NM_001130984.1, NM_001130980.1, NM_001130985.1, NM_001130978.1, NM_001130983.1, NM_001130979.1, NM_001130982.1, NM_001130981.1, NM_001130987.1, BC038246, BC171803, BC172229, NM_001130985.2, NM_001130977.2, NM_001130976.2, NM_001130986.2, NM_001130983.2, NM_001130982.2, NM_001130984.2, NM_001130979.2, NM_003494.4, NM_001130455.2, NM_001130987.2, NM_001130980.2, NM_001130981.2, NM_001130978.2 |
| UniProt ID | O75923 |
| Summary | The protein encoded by this gene belongs to the ferlin family and is a skeletal muscle protein found associated with the sarcolemma. It is involved in muscle contraction and contains C2 domains that play a role in calcium-mediated membrane fusion events, suggesting that it may be involved in membrane regeneration and repair. In addition, the protein encoded by this gene binds caveolin-3, a skeletal muscle membrane protein which is important in the formation of caveolae. Specific mutations in this gene have been shown to cause autosomal recessive limb girdle muscular dystrophy type 2B (LGMD2B) as well as Miyoshi myopathy. Alternative splicing results in multiple transcript variants. provided by RefSeq, Aug 2008 |
| shRNA Design | These shRNA constructs were designed against multiple splice variants at this gene locus. To be certain that your variant of interest is targeted, please contact techsupport@origene.com. If you need a special design or shRNA sequence, please utilize our custom shRNA service. |
| Shipping | Ambient |
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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen
complexities in the preparation of your product. International customers may expect an additional 1-2 weeks
in shipping.