EFEMP1 Human shRNA Plasmid Kit (Locus ID 2202)
SKU
TL313284
EFEMP1 - Human, 4 unique 29mer shRNA constructs in lentiviral GFP vector, 5µg of each construct provided
$1,013.00
In Stock*
Specifications
| Product Data | |
| Locus ID | 2202 |
|---|---|
| Synonyms | DHRD; DRAD; FBLN3; FBNL; FIBL-3; MLVT; MTLV; S1-5 |
| Vector | pGFP-C-shLenti |
| E. coli Selection | Chloramphenicol (34 ug/ml) |
| Mammalian Cell Selection | Puromycin |
| Format | Lentiviral plasmids |
| Components | EFEMP1 - Human, 4 unique 29mer shRNA constructs in lentiviral GFP vector(Gene ID = 2202). 5µg purified plasmid DNA per construct29-mer scrambled shRNA cassette in pGFP-C-shLenti Vector, TR30021, included for free. |
| RefSeq | NM_001039348, NM_001039349, NM_004105, NM_018894, NM_001039349.1, NM_001039349.2, NM_004105.1, NM_004105.2, NM_004105.3, NM_001039348.1, NM_001039348.2, BC014410, BC014410.1, BC098561, NM_001039349.3, NM_001039348.3 |
| UniProt ID | Q12805 |
| Summary | This gene encodes a member of the fibulin family of extracellular matrix glycoproteins. Like all members of this family, the encoded protein contains tandemly repeated epidermal growth factor-like repeats followed by a C-terminus fibulin-type domain. This gene is upregulated in malignant gliomas and may play a role in the aggressive nature of these tumors. Mutations in this gene are associated with Doyne honeycomb retinal dystrophy. Alternatively spliced transcript variants that encode the same protein have been described.provided by RefSeq, Nov 2009 |
| shRNA Design | These shRNA constructs were designed against multiple splice variants at this gene locus. To be certain that your variant of interest is targeted, please contact techsupport@origene.com. If you need a special design or shRNA sequence, please utilize our custom shRNA service. |
| Storage | Store at -20°C |
| Shipping | Ambient |
Reviews
Documents
Resources
Citations
The matrix protein Fibulin-3 promotes KISS1R induced triple negative breast cancer cell invasion
Noonan, Dragan, Mehta et al
Oncotarget (2018) 9 (53), 30034-30052 DOI: 10.18632/oncotarget.25682
Noonan, Dragan, Mehta et al
Oncotarget (2018) 9 (53), 30034-30052 DOI: 10.18632/oncotarget.25682
Snippet: Gene knockdown of fibulin-3 was achieved using lentivirus-delivered pGFP-C-shLenti shRNA cloning plasmid (Origene Technologies;Rockville, MD, USA). Heterogeneous populations of stable transfectants were selected using medium containing puromycin (1.5 µg/mL)
Fibulin-3 promotes muscle-invasive bladder cancer
Han, Veeneman, El-Sawy et al
Oncogene (2017)
Han, Veeneman, El-Sawy et al
Oncogene (2017)
AI Summary: OriGene’s anti-fibulin-3 antibody (TA503772) was used in this study to detect and validate fibulin-3 protein expression, supporting the investigation of its role in promoting muscle-invasive bladder cancer.
Snippet: Appropriate primary antibody was added after blocking for an hour with 5% non-fat milk: anti-fibulin-3 (TA503772, Origene, Rockville, MD, USA), anti-DUSP2 (sc-32776, Santa Cruz, Santa Cruz, CA, USA), anti-glut3 (GT33-A, Alpha Diagnostic Intl., San Antonio, TX, ... All 4 versions Cite SaveSaving
Showing 1-2 of 2 papers.
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