EIF4E Human shRNA Plasmid Kit (Locus ID 1977)
Specifications
| Product Data | |
| Locus ID | 1977 |
|---|---|
| Synonyms | AUTS19; CBP; eIF-4E; EIF4E1; EIF4EL1; EIF4F |
| Vector | pGFP-C-shLenti |
| E. coli Selection | Chloramphenicol (34 ug/ml) |
| Mammalian Cell Selection | Puromycin |
| Format | Lentiviral plasmids |
| Components | EIF4E - Human, 4 unique 29mer shRNA constructs in lentiviral GFP vector(Gene ID = 1977). 5µg purified plasmid DNA per construct29-mer scrambled shRNA cassette in pGFP-C-shLenti Vector, TR30021, included for free. |
| RefSeq | NM_001130678, NM_001130679, NM_001331017, NM_001968, NM_001968.1, NM_001968.2, NM_001968.3, NM_001968.4, NM_001130678.1, NM_001130678.2, NM_001130679.1, NM_001130679.2, BC035166, BC035166.1, BC012611, BC043226, BC107715, BM849222, NM_001130678.3 |
| UniProt ID | P06730 |
| Summary | The protein encoded by this gene is a component of the eukaryotic translation initiation factor 4F complex, which recognizes the 7-methylguanosine cap structure at the 5' end of messenger RNAs. The encoded protein aids in translation initiation by recruiting ribosomes to the 5'-cap structure. Association of this protein with the 4F complex is the rate-limiting step in translation initiation. This gene acts as a proto-oncogene, and its expression and activation is associated with transformation and tumorigenesis. Several pseudogenes of this gene are found on other chromosomes. Alternative splicing results in multiple transcript variants. provided by RefSeq, Sep 2015 |
| shRNA Design | These shRNA constructs were designed against multiple splice variants at this gene locus. To be certain that your variant of interest is targeted, please contact techsupport@origene.com. If you need a special design or shRNA sequence, please utilize our custom shRNA service. |
| Storage | Store at -20°C |
| Shipping | Ambient |
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