GATA6 Human shRNA Plasmid Kit (Locus ID 2627)

SKU
TL312832
GATA6 - Human, 4 unique 29mer shRNA constructs in lentiviral GFP vector, 5µg of each construct provided
  $1,013.00
In Stock*
Specifications
Specifications
Product Data
Locus ID 2627
Vector pGFP-C-shLenti
E. coli Selection Chloramphenicol (34 ug/ml)
Mammalian Cell Selection Puromycin
Format Lentiviral plasmids
Components GATA6 - Human, 4 unique 29mer shRNA constructs in lentiviral GFP vector(Gene ID = 2627). 5µg purified plasmid DNA per construct
29-mer scrambled shRNA cassette in pGFP-C-shLenti Vector, TR30021, included for free.
RefSeq NM_005257, NM_005257.1, NM_005257.2, NM_005257.3, NM_005257.4, NM_005257.5, BC027891, NM_005257.6
UniProt ID Q92908
Summary This gene is a member of a small family of zinc finger transcription factors that play an important role in the regulation of cellular differentiation and organogenesis during vertebrate development. This gene is expressed during early embryogenesis and localizes to endo- and mesodermally derived cells during later embryogenesis and thereby plays an important role in gut, lung, and heart development. Mutations in this gene are associated with several congenital defects. provided by RefSeq, Mar 2012
shRNA Design These shRNA constructs were designed against multiple splice variants at this gene locus. To be certain that your variant of interest is targeted, please contact techsupport@origene.com. If you need a special design or shRNA sequence, please utilize our custom shRNA service.
Storage Store at -20°C
Shipping Ambient
Reviews
 
 
 
 
 

Be the first to review this product

Please note:
Only reviews with images are eligible for a $20/20€ Amazon gift card.
Reviews without images are eligible for a $10/10€ Amazon gift card.
For more details about the terms and conditions, please visit the promotion page.

Review image
Documents
Resources

file-alt Citations

Human Pancreatic Tumor Organoids Reveal Loss of Stem Cell Niche Factor Dependence during Disease Progression
Seino, Kawasaki, Shimokawa et al
Cell Stem Cell (2018) 22 (3), 454-467.e6 DOI: 10.1016/j.stem.2017.12.009
Cited by 650
AI Summary: In this study, OriGene products—specifically the GATA6 shRNA (OriGene, TG311482) and GATA6 cDNA (OriGene, RC210307)—were used to manipulate GATA6 expression in pancreatic tumor organoids, enabling the authors to functionally investigate the role of GATA6 in determining Wnt niche factor dependency during PDAC progression.
Showing 1-1 of 1 papers.
Powered by BizGenius
*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

Related Products