GLRB Human shRNA Plasmid Kit (Locus ID 2743)
Specifications
| Product Data | |
| Locus ID | 2743 |
|---|---|
| Synonyms | HKPX2 |
| Vector | pGFP-C-shLenti |
| E. coli Selection | Chloramphenicol (34 ug/ml) |
| Mammalian Cell Selection | Puromycin |
| Format | Lentiviral plasmids |
| Components | GLRB - Human, 4 unique 29mer shRNA constructs in lentiviral GFP vector(Gene ID = 2743). 5µg purified plasmid DNA per construct29-mer scrambled shRNA cassette in pGFP-C-shLenti Vector, TR30021, included for free. |
| RefSeq | NM_000824, NM_001166060, NM_001166061, NM_000824.1, NM_000824.2, NM_000824.3, NM_000824.4, NM_001166061.1, NM_001166060.1, BC032635, BC032635.1, BC022502 |
| UniProt ID | P48167 |
| Summary | This gene encodes the beta subunit of the glycine receptor, which is a pentamer composed of alpha and beta subunits. The receptor functions as a neurotransmitter-gated ion channel, which produces hyperpolarization via increased chloride conductance due to the binding of glycine to the receptor. Mutations in this gene cause startle disease, also known as hereditary hyperekplexia or congenital stiff-person syndrome, a disease characterized by muscular rigidity. Alternative splicing results in multiple transcript variants. provided by RefSeq, Oct 2009 |
| shRNA Design | These shRNA constructs were designed against multiple splice variants at this gene locus. To be certain that your variant of interest is targeted, please contact techsupport@origene.com. If you need a special design or shRNA sequence, please utilize our custom shRNA service. |
| Storage | Store at -20°C |
| Shipping | Ambient |
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