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HDAC1 Human shRNA Plasmid Kit (Locus ID 3065)

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SKU
TL312496
HDAC1 - Human, 4 unique 29mer shRNA constructs in lentiviral GFP vector, 5µg of each construct provided
  $1,013.00
In Stock*

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Other products for "HDAC1 or NM_004964"

Specifications
Specifications
Product Data
Locus ID 3065
Synonyms GON-10; HD1; KDAC1; RPD3; RPD3L1
Vector pGFP-C-shLenti
E. coli Selection Chloramphenicol (34 ug/ml)
Mammalian Cell Selection Puromycin
Format Lentiviral plasmids
Components HDAC1 - Human, 4 unique 29mer shRNA constructs in lentiviral GFP vector(Gene ID = 3065). 5µg purified plasmid DNA per construct
29-mer scrambled shRNA cassette in pGFP-C-shLenti Vector, TR30021, included for free.
RefSeq NM_004964, NM_004964.1, NM_004964.2, BC000301, BC000301.2, NM_004964.3
UniProt ID Q13547
Summary Histone acetylation and deacetylation, catalyzed by multisubunit complexes, play a key role in the regulation of eukaryotic gene expression. The protein encoded by this gene belongs to the histone deacetylase/acuc/apha family and is a component of the histone deacetylase complex. It also interacts with retinoblastoma tumor-suppressor protein and this complex is a key element in the control of cell proliferation and differentiation. Together with metastasis-associated protein-2, it deacetylates p53 and modulates its effect on cell growth and apoptosis. provided by RefSeq, Jul 2008
shRNA Design These shRNA constructs were designed against multiple splice variants at this gene locus. To be certain that your variant of interest is targeted, please contact techsupport@origene.com. If you need a special design or shRNA sequence, please utilize our custom shRNA service.
Storage Store at -20°C
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Documents
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file-alt Citations

The histone deacetylase HDAC1 controls dendritic cell development and anti-tumor immunity
De Sá Fernandes, Novoszel, Gastaldi et al
Cell Rep (2024) 43 (6), 114308 DOI: 10.1016/j.celrep.2024.114308
Cited by 31
AI Summary: OriGene’s HDAC1 Human shRNA plasmid Kit (Locus ID 3065) was used in this study to knock down HDAC1 expression in human hematopoietic cells, enabling the authors to assess HDAC1’s role in dendritic cell development and anti-tumor immunity.
Snippet: HDAC1 Human shRNA plasmid Kit (Locus ID 3065) Origene TL312496 Chemicals, peptides, and recombinant proteins Liberase TM Sigma-aldrich 5401127001
Histone deacetylase 1 facilitates aerobic glycolysis and growth of endometrial cancer
Wu, Zhang, Liu et al
Oncol Lett (2021) 22 (4), 721 DOI: 10.3892/ol.2021.12982
Cited by 13
AI Summary: OriGene products, specifically the HDAC1 overexpression plasmid (cat. no. RC201745L4V) and HDAC1 shRNA (cat. no. TL312496V), were used to manipulate HDAC1 levels in endometrial cancer cells, enabling the study of HDAC1's role in cancer cell metabolism and progression.
Snippet: cells are termed overexpression (OE)-HDAC1 (cat. no. RC201745L4V) and short hairpin (sh)-HDAC1 (cat. no. TL312496V), and were purchased from OriGene Technologies, Inc. 293T cells were used to generate the virions
FigureFigureFigure
Showing 1-2 of 2 papers.
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