HGF Human shRNA Plasmid Kit (Locus ID 3082)

SKU TL312467

HGF - Human, 4 unique 29mer shRNA constructs in lentiviral GFP vector, 5µg of each construct provided

Product Data

• Locus ID: 3082
• Synonyms: DFNB39; F-TCF; HGFB; HPTA; SF
• Vector: pGFP-C-shLenti
• E. coli Selection: Chloramphenicol (34 ug/ml)
• Format: Lentiviral plasmids
• Components: HGF - Human, 4 unique 29mer shRNA constructs in lentiviral GFP vector(Gene ID = 3082). 5µg purified plasmid DNA per construct; 29-mer scrambled shRNA cassette in pGFP-C-shLenti Vector, TR30021, included for free.
• RefSeq: NM_000601, NM_001010931, NM_001010932, NM_001010933, NM_001010934, NM_001010931.1, NM_001010931.2, NM_001010933.1, NM_001010933.2, NM_000601.2, NM_000601.3, NM_000601.4, NM_000601.5, NM_001010934.1, NM_001010934.2, NM_001010932.1, NM_001010932.2, BC022308, BC063485, BC105797, BC130284, BC130286, BM153501, BM971901, NM_001010931.3, NM_000601.6, NM_001010933.3, NM_001010934.3, NM_001010932.3
• UniProt ID: P14210
• Summary: This gene encodes a protein that binds to the hepatocyte growth factor receptor to regulate cell growth, cell motility and morphogenesis in numerous cell and tissue types. Alternative splicing results in multiple transcript variants, at least one of which encodes a preproprotein that is proteolytically processed to generate alpha and beta chains, which form the mature heterodimer. This protein is secreted by mesenchymal cells and acts as a multi-functional cytokine on cells of mainly epithelial origin. This protein also plays a role in angiogenesis, tumorogenesis, and tissue regeneration. Although the encoded protein is a member of the peptidase S1 family of serine proteases, it lacks peptidase activity. Mutations in this gene are associated with nonsyndromic hearing loss. [provided by RefSeq, Nov 2015]
• shRNA Design: These shRNA constructs were designed against multiple splice variants at this gene locus. To be certain that your variant of interest is targeted, please contact techsupport@origene.com. If you need a special design or shRNA sequence, please utilize our custom shRNA service.
• Shipping: Ambient