IL17RA Human shRNA Plasmid Kit (Locus ID 23765)
Specifications
| Product Data | |
| Locus ID | 23765 |
|---|---|
| Synonyms | CANDF5; CD217; CDw217; hIL-17R; IL-17RA; IL17R; IMD51 |
| Vector | pGFP-C-shLenti |
| E. coli Selection | Chloramphenicol (34 ug/ml) |
| Mammalian Cell Selection | Puromycin |
| Format | Lentiviral plasmids |
| Components | IL17RA - Human, 4 unique 29mer shRNA constructs in lentiviral GFP vector(Gene ID = 23765). 5µg purified plasmid DNA per construct29-mer scrambled shRNA cassette in pGFP-C-shLenti Vector, TR30021, included for free. |
| RefSeq | NM_001289905, NM_014339, NM_014339.1, NM_014339.2, NM_014339.3, NM_014339.4, NM_014339.5, NM_014339.6, NM_001289905.1, BC011624, BC011624.2, BC012071 |
| UniProt ID | Q96F46 |
| Summary | Interleukin 17A (IL17A) is a proinflammatory cytokine secreted by activated T-lymphocytes. It is a potent inducer of the maturation of CD34-positive hematopoietic precursors into neutrophils. The transmembrane protein encoded by this gene (interleukin 17A receptor; IL17RA) is a ubiquitous type I membrane glycoprotein that binds with low affinity to interleukin 17A. Interleukin 17A and its receptor play a pathogenic role in many inflammatory and autoimmune diseases such as rheumatoid arthritis. Like other cytokine receptors, this receptor likely has a multimeric structure. Alternative splicing results in multiple transcript variants encoding different isoforms. provided by RefSeq, Feb 2014 |
| shRNA Design | These shRNA constructs were designed against multiple splice variants at this gene locus. To be certain that your variant of interest is targeted, please contact techsupport@origene.com. If you need a special design or shRNA sequence, please utilize our custom shRNA service. |
| Storage | Store at -20°C |
| Shipping | Ambient |
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