LITAF Human shRNA Plasmid Kit (Locus ID 9516)
Specifications
| Product Data | |
| Locus ID | 9516 |
|---|---|
| Synonyms | PIG7; SIMPLE; TP53I7 |
| Vector | pGFP-C-shLenti |
| E. coli Selection | Chloramphenicol (34 ug/ml) |
| Mammalian Cell Selection | Puromycin |
| Format | Lentiviral plasmids |
| Components | LITAF - Human, 4 unique 29mer shRNA constructs in lentiviral GFP vector(Gene ID = 9516). 5µg purified plasmid DNA per construct29-mer scrambled shRNA cassette in pGFP-C-shLenti Vector, TR30021, included for free. |
| RefSeq | NM_001136472, NM_001136473, NM_004862, NR_024320, NM_004862.1, NM_004862.2, NM_004862.3, NM_001136472.1, NM_001136473.1, BC016491, BC000053, BC008309, BC039840, BC046154, BC065293, BC096063, BC096064, BC096065, BC096066, BC101401, BC101402, BC101969, BC107713 |
| UniProt ID | Q99732 |
| Summary | Lipopolysaccharide is a potent stimulator of monocytes and macrophages, causing secretion of tumor necrosis factor-alpha (TNF-alpha) and other inflammatory mediators. This gene encodes lipopolysaccharide-induced TNF-alpha factor, which is a DNA-binding protein and can mediate the TNF-alpha expression by direct binding to the promoter region of the TNF-alpha gene. The transcription of this gene is induced by tumor suppressor p53 and has been implicated in the p53-induced apoptotic pathway. Mutations in this gene cause Charcot-Marie-Tooth disease type 1C (CMT1C) and may be involved in the carcinogenesis of extramammary Paget's disease (EMPD). Multiple alternatively spliced transcript variants have been found for this gene. provided by RefSeq, Dec 2014 |
| shRNA Design | These shRNA constructs were designed against multiple splice variants at this gene locus. To be certain that your variant of interest is targeted, please contact techsupport@origene.com. If you need a special design or shRNA sequence, please utilize our custom shRNA service. |
| Storage | Store at -20°C |
| Shipping | Ambient |
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