LRRFIP1 Human shRNA Plasmid Kit (Locus ID 9208)
Specifications
| Product Data | |
| Locus ID | 9208 |
|---|---|
| Synonyms | FLAP-1; FLAP1; FLIIAP1; GCF-2; GCF2; HUFI-1; TRIP |
| Vector | pGFP-C-shLenti |
| E. coli Selection | Chloramphenicol (34 ug/ml) |
| Mammalian Cell Selection | Puromycin |
| Format | Lentiviral plasmids |
| Components | LRRFIP1 - Human, 4 unique 29mer shRNA constructs in lentiviral GFP vector(Gene ID = 9208). 5µg purified plasmid DNA per construct29-mer scrambled shRNA cassette in pGFP-C-shLenti Vector, TR30021, included for free. |
| RefSeq | NM_001137550, NM_001137551, NM_001137552, NM_001137553, NM_004735, NM_032674, NM_004735.1, NM_004735.2, NM_004735.3, NM_001137551.1, NM_001137552.1, NM_001137553.1, NM_001137550.1, BC108914, BC108913, BC001385, BC004958, BC010662, BC018883, BC019335, BC071618, BC083492, NM_001137553.2, NM_004735.4, NM_001137550.2 |
| UniProt ID | Q32MZ4 |
| Summary | Transcriptional repressor which preferentially binds to the GC-rich consensus sequence (5'-AGCCCCCGGCG-3') and may regulate expression of TNF, EGFR and PDGFA. May control smooth muscle cells proliferation following artery injury through PDGFA repression. May also bind double-stranded RNA. Positively regulates Toll-like receptor (TLR) signaling in response to agonist probably by competing with the negative FLII regulator for MYD88-binding.UniProtKB/Swiss-Prot Function |
| shRNA Design | These shRNA constructs were designed against multiple splice variants at this gene locus. To be certain that your variant of interest is targeted, please contact techsupport@origene.com. If you need a special design or shRNA sequence, please utilize our custom shRNA service. |
| Storage | Store at -20°C |
| Shipping | Ambient |
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