MNAT1 Human shRNA Plasmid Kit (Locus ID 4331)

SKU
TL311433
MNAT1 - Human, 4 unique 29mer shRNA constructs in lentiviral GFP vector, 5µg of each construct provided
  $1,013.00
2 Weeks*
Specifications
Specifications
Product Data
Locus ID 4331
Synonyms CAP35; MAT1; RNF66; TFB3
Vector pGFP-C-shLenti
E. coli Selection Chloramphenicol (34 ug/ml)
Mammalian Cell Selection Puromycin
Format Lentiviral plasmids
Components MNAT1 - Human, 4 unique 29mer shRNA constructs in lentiviral GFP vector(Gene ID = 4331). 5µg purified plasmid DNA per construct
29-mer scrambled shRNA cassette in pGFP-C-shLenti Vector, TR30021, included for free.
RefSeq NM_001177963, NM_002431, NM_002431.1, NM_002431.2, NM_002431.3, NM_001177963.1, BC000820, BC000820.1, NM_001177963.2, NM_002431.4
UniProt ID P51948
Summary The protein encoded by this gene, along with cyclin H and CDK7, forms the CDK-activating kinase (CAK) enzymatic complex. This complex activates several cyclin-associated kinases and can also associate with TFIIH to activate transcription by RNA polymerase II. Two transcript variants encoding different isoforms have been found for this gene. provided by RefSeq, Sep 2011
shRNA Design These shRNA constructs were designed against multiple splice variants at this gene locus. To be certain that your variant of interest is targeted, please contact techsupport@origene.com. If you need a special design or shRNA sequence, please utilize our custom shRNA service.
Storage Store at -20°C
Shipping Ambient
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Documents
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file-alt Citations

MAT1 facilitates the lung metastasis of osteosarcoma through upregulation of AKT1 expression
Wang, Ni, Song et al
Life Sci. (2019) 234, 116771 DOI: 10.1016/j.lfs.2019.116771
AI Summary: OriGene products sh-AKT1 (No. TL320260) and sh-MAT1 (No. TL311433) were used in this study to specifically downregulate AKT1 and MAT1 gene expression, enabling the authors to investigate the roles of these genes in osteosarcoma cell migration, invasion, and metastasis.
Snippet: ShRNAs targeting the human AKT1 gene (sh-AKT1;No. TL320260) and MAT1 gene (sh-MAT1;No. TL311433) were purchased from OriGene (Beijing, China) and used to downregulate AKT1 and MAT1, respectively. 2.4. Real time quantitative PCR (RT-PCR);
Showing 1-1 of 1 papers.
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