NOB1 Human shRNA Plasmid Kit (Locus ID 28987)
Specifications
| Product Data | |
| Locus ID | 28987 |
|---|---|
| Synonyms | ART-4; MST158; MSTP158; NOB1P; PSMD8BP1 |
| Vector | pGFP-C-shLenti |
| E. coli Selection | Chloramphenicol (34 ug/ml) |
| Mammalian Cell Selection | Puromycin |
| Format | Lentiviral plasmids |
| Components | NOB1 - Human, 4 unique 29mer shRNA constructs in lentiviral GFP vector(Gene ID = 28987). 5µg purified plasmid DNA per construct29-mer scrambled shRNA cassette in pGFP-C-shLenti Vector, TR30021, included for free. |
| RefSeq | NM_014062, NR_074074, NM_014062.1, NM_014062.2, BC064630, BC064630.1, BC000050, BM793847, BM827373, NM_014062.3 |
| UniProt ID | Q9ULX3 |
| Summary | In yeast, over 200 protein and RNA cofactors are required for ribosome assembly, and these are generally conserved in eukaryotes. These factors orchestrate modification and cleavage of the initial 35S precursor rRNA transcript into the mature 18S, 5.8S, and 25S rRNAs, folding of the rRNA, and binding of ribosomal proteins and 5S RNA. Nob1 is involved in pre-rRNA processing. In a late cytoplasmic processing step, Nob1 cleaves a 20S rRNA intermediate at cleavage site D to produce the mature 18S rRNA (Lamanna and Karbstein, 2009 PubMed 19706509).supplied by OMIM, Nov 2010 |
| shRNA Design | These shRNA constructs were designed against multiple splice variants at this gene locus. To be certain that your variant of interest is targeted, please contact techsupport@origene.com. If you need a special design or shRNA sequence, please utilize our custom shRNA service. |
| Storage | Store at -20°C |
| Shipping | Ambient |
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