REA (PHB2) Human shRNA Plasmid Kit (Locus ID 11331)
Specifications
| Product Data | |
| Locus ID | 11331 |
|---|---|
| Synonyms | BAP; Bap37; BCAP37; hBAP; p22; PNAS-141; REA |
| Vector | pGFP-C-shLenti |
| E. coli Selection | Chloramphenicol (34 ug/ml) |
| Mammalian Cell Selection | Puromycin |
| Format | Lentiviral plasmids |
| Components | PHB2 - Human, 4 unique 29mer shRNA constructs in lentiviral GFP vector(Gene ID = 11331). 5µg purified plasmid DNA per construct29-mer scrambled shRNA cassette in pGFP-C-shLenti Vector, TR30021, included for free. |
| RefSeq | NM_001144831, NM_001267700, NM_007273, NM_001144831.1, NM_001267700.1, NM_007273.3, BC110322, BC110322.1, BC013228, BC014766, NM_001144831.2 |
| UniProt ID | Q99623 |
| Summary | Acts as a mediator of transcriptional repression by nuclear hormone receptors via recruitment of histone deacetylases (By similarity). Functions as an estrogen receptor (ER)-selective coregulator that potentiates the inhibitory activities of antiestrogens and represses the activity of estrogens. Competes with NCOA1 for modulation of ER transcriptional activity. In mitochondria, regulates cytochrome-c oxidase assembly (COX) and mitochondrial respiration. Binding to sphingoid 1-phosphate (SPP) modulates its regulator activity (PubMed:20959514).UniProtKB/Swiss-Prot Function |
| shRNA Design | These shRNA constructs were designed against multiple splice variants at this gene locus. To be certain that your variant of interest is targeted, please contact techsupport@origene.com. If you need a special design or shRNA sequence, please utilize our custom shRNA service. |
| Storage | Store at -20°C |
| Shipping | Ambient |
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