PMVK Human shRNA Plasmid Kit (Locus ID 10654)
Specifications
| Product Data | |
| Locus ID | 10654 |
|---|---|
| Synonyms | HUMPMKI; PMK; PMKA; PMKASE; POROK1 |
| Vector | pGFP-C-shLenti |
| E. coli Selection | Chloramphenicol (34 ug/ml) |
| Mammalian Cell Selection | Puromycin |
| Format | Lentiviral plasmids |
| Components | PMVK - Human, 4 unique 29mer shRNA constructs in lentiviral GFP vector(Gene ID = 10654). 5µg purified plasmid DNA per construct29-mer scrambled shRNA cassette in pGFP-C-shLenti Vector, TR30021, included for free. |
| RefSeq | NM_006556, NM_001323011, NM_001323012, NM_001348696, NM_006556.1, NM_006556.2, NM_006556.3, BC006089, BC006089.1, BC007694, NM_006556.4 |
| UniProt ID | Q15126 |
| Summary | This gene encodes a peroxisomal enzyme that is a member of the galactokinase, homoserine kinase, mevalonate kinase, and phosphomevalonate kinase (GHMP) family of ATP-dependent enzymes. The encoded protein catalyzes the conversion of mevalonate 5-phosphate to mevalonate 5-diphosphate, which is the fifth step in the mevalonate pathway of isoprenoid biosynthesis. Mutations in this gene are linked to certain types of porokeratosis including disseminated superficial porokeratosis. Alternative splicing results in multiple transcript variants. provided by RefSeq, Feb 2017 |
| shRNA Design | These shRNA constructs were designed against multiple splice variants at this gene locus. To be certain that your variant of interest is targeted, please contact techsupport@origene.com. If you need a special design or shRNA sequence, please utilize our custom shRNA service. |
| Storage | Store at -20°C |
| Shipping | Ambient |
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