PSMB5 Human shRNA Plasmid Kit (Locus ID 5693)
SKU
TL310110
PSMB5 - Human, 4 unique 29mer shRNA constructs in lentiviral GFP vector, 5µg of each construct provided
$1,013.00
2 Weeks*
Specifications
| Product Data | |
| Locus ID | 5693 |
|---|---|
| Synonyms | LMPX; MB1; X |
| Vector | pGFP-C-shLenti |
| E. coli Selection | Chloramphenicol (34 ug/ml) |
| Mammalian Cell Selection | Puromycin |
| Format | Lentiviral plasmids |
| Components | PSMB5 - Human, 4 unique 29mer shRNA constructs in lentiviral GFP vector(Gene ID = 5693). 5µg purified plasmid DNA per construct29-mer scrambled shRNA cassette in pGFP-C-shLenti Vector, TR30021, included for free. |
| RefSeq | NM_001130725, NM_001144932, NM_002797, NM_002797.1, NM_002797.2, NM_002797.3, NM_002797.4, NM_001130725.1, NM_001144932.1, NM_001144932.2, BC057840, BC057840.1, BC107720, NM_002797.5 |
| UniProt ID | P28074 |
| Summary | The proteasome is a multicatalytic proteinase complex with a highly ordered ring-shaped 20S core structure. The core structure is composed of 4 rings of 28 non-identical subunits; 2 rings are composed of 7 alpha subunits and 2 rings are composed of 7 beta subunits. Proteasomes are distributed throughout eukaryotic cells at a high concentration and cleave peptides in an ATP/ubiquitin-dependent process in a non-lysosomal pathway. An essential function of a modified proteasome, the immunoproteasome, is the processing of class I MHC peptides. This gene encodes a member of the proteasome B-type family, also known as the T1B family, that is a 20S core beta subunit in the proteasome. This catalytic subunit is not present in the immunoproteasome and is replaced by catalytic subunit 3i (proteasome beta 8 subunit). Multiple transcript variants encoding different isoforms have been found for this gene. provided by RefSeq, Jan 2009 |
| shRNA Design | These shRNA constructs were designed against multiple splice variants at this gene locus. To be certain that your variant of interest is targeted, please contact techsupport@origene.com. If you need a special design or shRNA sequence, please utilize our custom shRNA service. |
| Storage | Store at -20°C |
| Shipping | Ambient |
Reviews
Documents
Resources
Citations
Inhibition of store-operated calcium entry by sub-lethal levels of proteasome inhibition is associated with STIM1/STIM2 degradation
Kuang, Liu, Chang et al
Cell Calcium (2016)
Kuang, Liu, Chang et al
Cell Calcium (2016)
Cited by 17
AI Summary: OriGene contributed to this study by providing the psmb5 shRNA lentivirus transfer plasmid, which was used to decrease proteasome subunit beta type-5 levels and assess its effects on calcium entry and protein degradation in neurons.
Snippet: film (Thermo Scientific Branch, Shanghai, PR China);Pierce ECL Western Blotting Substrate (Thermo Scientific, Rockford, IL);protease inhibitor cocktail (Calbiochem, San Diego, CA);psmb5 shRNA lentivirus transfer plasmid carrying GFP fluorescence (Origene, Rockville ... Cite SaveSaving
Showing 1-1 of 1 papers.
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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen
complexities in the preparation of your product. International customers may expect an additional 1-2 weeks
in shipping.
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