QDPR Human shRNA Plasmid Kit (Locus ID 5860)
Specifications
| Product Data | |
| Locus ID | 5860 |
|---|---|
| Synonyms | DHPR; HDHPR; PKU2; SDR33C1 |
| Vector | pGFP-C-shLenti |
| E. coli Selection | Chloramphenicol (34 ug/ml) |
| Mammalian Cell Selection | Puromycin |
| Format | Lentiviral plasmids |
| Components | QDPR - Human, 4 unique 29mer shRNA constructs in lentiviral GFP vector(Gene ID = 5860). 5µg purified plasmid DNA per construct29-mer scrambled shRNA cassette in pGFP-C-shLenti Vector, TR30021, included for free. |
| RefSeq | BC000576, NM_000320, NM_001306140, NM_000320.1, NM_000320.2, BC000576.2, BM760507, BM762805, NR_156494, NM_000320.3 |
| UniProt ID | P09417 |
| Summary | This gene encodes the enzyme dihydropteridine reductase, which catalyzes the NADH-mediated reduction of quinonoid dihydrobiopterin. This enzyme is an essential component of the pterin-dependent aromatic amino acid hydroxylating systems. Mutations in this gene resulting in QDPR deficiency include aberrant splicing, amino acid substitutions, insertions, or premature terminations. Dihydropteridine reductase deficiency presents as atypical phenylketonuria due to insufficient production of biopterin, a cofactor for phenylalanine hydroxylase. provided by RefSeq, Jul 2008 |
| shRNA Design | These shRNA constructs were designed against multiple splice variants at this gene locus. To be certain that your variant of interest is targeted, please contact techsupport@origene.com. If you need a special design or shRNA sequence, please utilize our custom shRNA service. |
| Storage | Store at -20°C |
| Shipping | Ambient |
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