RASAL1 Human shRNA Plasmid Kit (Locus ID 8437)
Specifications
| Product Data | |
| Locus ID | 8437 |
|---|---|
| Synonyms | RASAL |
| Vector | pGFP-C-shLenti |
| E. coli Selection | Chloramphenicol (34 ug/ml) |
| Mammalian Cell Selection | Puromycin |
| Format | Lentiviral plasmids |
| Components | RASAL1 - Human, 4 unique 29mer shRNA constructs in lentiviral GFP vector(Gene ID = 8437). 5µg purified plasmid DNA per construct29-mer scrambled shRNA cassette in pGFP-C-shLenti Vector, TR30021, included for free. |
| RefSeq | NM_001193520, NM_001193521, NM_001301202, NM_004658, NM_004658.1, NM_004658.2, NM_001193521.1, NM_001193520.1, NM_001301202.1, BC093724, BC093724.1, BC014420, BC143258, BC143261, BC143262 |
| UniProt ID | O95294 |
| Summary | The protein encoded by this gene is member of the GAP1 family of GTPase-activating proteins. These proteins stimulate the GTPase activity of normal RAS p21 but not its oncogenic counterpart. Acting as a suppressor of RAS function, the protein enhances the weak intrinsic GTPase activity of RAS proteins resulting in the inactive GDP-bound form of RAS, thereby allowing control of cellular proliferation and differentiation. This particular family member contains domains which are characteristic of the GAP1 subfamily of RasGAP proteins but, in contrast to the other GAP1 family members, this protein is strongly and selectively expressed in endocrine tissues. Alternatively spliced transcript variants that encode different isoforms have been described provided by RefSeq, Jul 2010 |
| shRNA Design | These shRNA constructs were designed against multiple splice variants at this gene locus. To be certain that your variant of interest is targeted, please contact techsupport@origene.com. If you need a special design or shRNA sequence, please utilize our custom shRNA service. |
| Storage | Store at -20°C |
| Shipping | Ambient |
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