SCAP2 (SKAP2) Human shRNA Plasmid Kit (Locus ID 8935)
Specifications
| Product Data | |
| Locus ID | 8935 |
|---|---|
| Synonyms | PRAP; RA70; SAPS; SCAP2; SKAP-HOM; SKAP55R |
| Vector | pGFP-C-shLenti |
| E. coli Selection | Chloramphenicol (34 ug/ml) |
| Mammalian Cell Selection | Puromycin |
| Format | Lentiviral plasmids |
| Components | SKAP2 - Human, 4 unique 29mer shRNA constructs in lentiviral GFP vector(Gene ID = 8935). 5µg purified plasmid DNA per construct29-mer scrambled shRNA cassette in pGFP-C-shLenti Vector, TR30021, included for free. |
| RefSeq | NM_001303468, NM_003930, NM_003930.1, NM_003930.2, NM_003930.3, NM_003930.4, BC036044, BC036044.1, BC002893, NM_003930.5 |
| UniProt ID | O75563 |
| Summary | The protein encoded by this gene shares homology with Src kinase-associated phosphoprotein 1, and is a substrate of Src family kinases. It is an adaptor protein that is thought to play an essential role in the Src signaling pathway, and in regulating proper activation of the immune system. This protein contains an amino terminal coiled-coil domain for self-dimerization, a plecskstrin homology (PH) domain required for interactions with lipids at the membrane, and a Src homology (SH3) domain at the carboxy terminus. Some reports indicate that this protein inhibits actin polymerization through interactions with actin assembly factors, and might negatively regulate the invasiveness of tumors by modulating actin assembly. Alternative splicing results in multiple transcript variants encoding different isoforms. provided by RefSeq, Jan 2015 |
| shRNA Design | These shRNA constructs were designed against multiple splice variants at this gene locus. To be certain that your variant of interest is targeted, please contact techsupport@origene.com. If you need a special design or shRNA sequence, please utilize our custom shRNA service. |
| Storage | Store at -20°C |
| Shipping | Ambient |
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