SEC31A Human shRNA Plasmid Kit (Locus ID 22872)

SKU
TL309573
SEC31A - Human, 4 unique 29mer shRNA constructs in lentiviral GFP vector, 5µg of each construct provided
In Control Promo
  $1,013.00
2 Weeks*
Specifications
Specifications
Product Data
Locus ID 22872
Synonyms ABP125; ABP130; HSPC275; HSPC334; NEDSOSB; SEC31L1
Vector pGFP-C-shLenti
E. coli Selection Chloramphenicol (34 ug/ml)
Mammalian Cell Selection Puromycin
Format Lentiviral plasmids
Components SEC31A - Human, 4 unique 29mer shRNA constructs in lentiviral GFP vector(Gene ID = 22872). 5µg purified plasmid DNA per construct
29-mer scrambled shRNA cassette in pGFP-C-shLenti Vector, TR30021, included for free.
RefSeq NM_001077206, NM_001077207, NM_001077208, NM_001191049, NM_001300744, NM_001300745, NM_001318119, NM_001318120, NM_014933, NM_016211, NM_001077206.1, NM_001077206.2, NM_001077206.3, NM_014933.1, NM_014933.2, NM_014933.3, NM_016211.1, NM_016211.2, NM_016211.3, NM_016211.4, NM_001077208.1, NM_001077208.2, NM_001077208.3, NM_001077207.1, NM_001077207.2, NM_001191049.1, NM_001191049.2, NM_001300744.1, NM_001300744.2, NM_001300745.1, NM_001300745.2, BC084583, BC084583.1, BC117221, BC031292, BC039834, BC047883, BC143489, BC143491, BC143492, BM677531
UniProt ID O94979
Summary The protein encoded by this gene shares similarity with the yeast Sec31 protein, and is a component of the outer layer of the coat protein complex II (COPII). The encoded protein is involved in vesicle budding from the endoplasmic reticulum (ER) and contains multiple WD repeats near the N-terminus and a proline-rich region in the C-terminal half. It associates with the protein encoded by the SEC13 homolog, nuclear pore and COPII coat complex component (SEC13), and is required for ER-Golgi transport. Monoubiquitylation of this protein by CUL3-KLHL12 was found to regulate the size of COPII coats to accommodate unusually shaped cargo. Alternative splicing results in multiple transcript variants encoding different isoforms. provided by RefSeq, Dec 2015
shRNA Design These shRNA constructs were designed against multiple splice variants at this gene locus. To be certain that your variant of interest is targeted, please contact techsupport@origene.com. If you need a special design or shRNA sequence, please utilize our custom shRNA service.
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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.