SEC31A Human shRNA Plasmid Kit (Locus ID 22872)
Specifications
| Product Data | |
| Locus ID | 22872 |
|---|---|
| Synonyms | ABP125; ABP130; HSPC275; HSPC334; NEDSOSB; SEC31L1 |
| Vector | pGFP-C-shLenti |
| E. coli Selection | Chloramphenicol (34 ug/ml) |
| Mammalian Cell Selection | Puromycin |
| Format | Lentiviral plasmids |
| Components | SEC31A - Human, 4 unique 29mer shRNA constructs in lentiviral GFP vector(Gene ID = 22872). 5µg purified plasmid DNA per construct29-mer scrambled shRNA cassette in pGFP-C-shLenti Vector, TR30021, included for free. |
| RefSeq | NM_001077206, NM_001077207, NM_001077208, NM_001191049, NM_001300744, NM_001300745, NM_001318119, NM_001318120, NM_014933, NM_016211, NM_001077206.1, NM_001077206.2, NM_001077206.3, NM_014933.1, NM_014933.2, NM_014933.3, NM_016211.1, NM_016211.2, NM_016211.3, NM_016211.4, NM_001077208.1, NM_001077208.2, NM_001077208.3, NM_001077207.1, NM_001077207.2, NM_001191049.1, NM_001191049.2, NM_001300744.1, NM_001300744.2, NM_001300745.1, NM_001300745.2, BC084583, BC084583.1, BC117221, BC031292, BC039834, BC047883, BC143489, BC143491, BC143492, BM677531 |
| UniProt ID | O94979 |
| Summary | The protein encoded by this gene shares similarity with the yeast Sec31 protein, and is a component of the outer layer of the coat protein complex II (COPII). The encoded protein is involved in vesicle budding from the endoplasmic reticulum (ER) and contains multiple WD repeats near the N-terminus and a proline-rich region in the C-terminal half. It associates with the protein encoded by the SEC13 homolog, nuclear pore and COPII coat complex component (SEC13), and is required for ER-Golgi transport. Monoubiquitylation of this protein by CUL3-KLHL12 was found to regulate the size of COPII coats to accommodate unusually shaped cargo. Alternative splicing results in multiple transcript variants encoding different isoforms. provided by RefSeq, Dec 2015 |
| shRNA Design | These shRNA constructs were designed against multiple splice variants at this gene locus. To be certain that your variant of interest is targeted, please contact techsupport@origene.com. If you need a special design or shRNA sequence, please utilize our custom shRNA service. |
| Storage | Store at -20°C |
| Shipping | Ambient |
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