SHMT2 Human shRNA Plasmid Kit (Locus ID 6472)

SKU TL309453

SHMT2 - Human, 4 unique 29mer shRNA constructs in lentiviral GFP vector, 5µg of each construct provided

Product Data

• Locus ID: 6472
• Synonyms: GLYA; HEL-S-51e; NEDCASB; SHMT
• Vector: pGFP-C-shLenti
• E. coli Selection: Chloramphenicol (34 ug/ml)
• Format: Lentiviral plasmids
• Components: SHMT2 - Human, 4 unique 29mer shRNA constructs in lentiviral GFP vector(Gene ID = 6472). 5µg purified plasmid DNA per construct; 29-mer scrambled shRNA cassette in pGFP-C-shLenti Vector, TR30021, included for free.
• RefSeq: BC032584, NM_001166356, NM_001166357, NM_001166358, NM_001166359, NM_005412, NR_029415, NR_029416, NR_029417, NR_048562, NM_005412.1, NM_005412.2, NM_005412.3, NM_005412.4, NM_005412.5, NM_001166359.1, NM_001166357.1, NM_001166358.1, NM_001166356.1, BC032584.1, BC011911, BC011911.2, BC008066, BC008711, BC013677, BC025355, BC044211, BC091501, NM_001166356.2, NM_005412.6
• UniProt ID: P34897
• Summary: This gene encodes the mitochondrial form of a pyridoxal phosphate-dependent enzyme that catalyzes the reversible reaction of serine and tetrahydrofolate to glycine and 5,10-methylene tetrahydrofolate. The encoded product is primarily responsible for glycine synthesis. The activity of the encoded protein has been suggested to be the primary source of intracellular glycine. The gene which encodes the cytosolic form of this enzyme is located on chromosome 17. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Oct 2009]
• shRNA Design: These shRNA constructs were designed against multiple splice variants at this gene locus. To be certain that your variant of interest is targeted, please contact techsupport@origene.com. If you need a special design or shRNA sequence, please utilize our custom shRNA service.
• Shipping: Ambient